The Conner family is thrown back together in a haze of blood and confusion, as prodigal son Griffin returns to his second family home - Bethune General Hospital.

Bruno shocks everyone by making an obscure diagnosis that saves a patient’s life, and a momentous secret from his past is revealed. After being kicked by a patient, Sandy calls Melissa for help instead of Brian.

Sandy struggles to say goodbye to Brian as her reconfigured family rally around to support her. Zoe and Griffin organize a labour stoppage after Lonnie is fired.

When an injured firefighter develops curious and frightening post-op symptoms, Mel and Jerry clash over how to proceed.

Mel explores the significance of a literal and figurative broken heart, while Griffin embarks on a drug-fueled odyssey.