Bruce Banner's latest attempt to rid himself of the Hulk is shut down by General Ross and Major Talbot. Now being held in the Gamma Base, Bruce recalls how he became the Incredible Hulk.

On the run from General Ross, Hulk encounters the Gamma Mutant Warriors. But Abomination reappears and captures Bruce. He is taken to The Leader, who wants the power of the Hulk for himself.

Ghost Rider is after the Hulk and so it Talbot, who has a deadly new weapon at his disposal.

Bruce is visiting his cousin, Jennifer Walters, in Washington D.C. But Doctor Doom attacks and captures them, leaving Jennifer needs a blood transfusion. Only Bruce can donate and Jennifer becomes She-Hulk.

Bruce and She-Hulk seek the help of Reed Richards, but instead find the Thing alone at Four Freedoms Plaza. With the other members of the Fantastic Four on vacation, it's up to the Thing, Hulk and She-Hulk to defeat the Ogress and The Leader's Gamma Warriors.

Betty and Doc Samson have found a way to seperate Bruce from the Hulk. All they need now is to smuggle the Hulk into the Gamma Base lab where the Nutrient Bath is waiting.

The Nutrient Bath has left Rick Jones transformed into a rampaging teenage Hulk and Bruce turning into a Gray Hulk. Bruce now faces a charge of attempted murder and his lawyer is Jennifer Walters (aka She-Hulk). Meanwhile, The Leader has a plan to capture Rick Jones and suppress Bruce's mind within Gray Hulk.

Miss Allure and Crusher Creel are making Chicago's crime world an even nastier place. To stop them, She-Hulk masquerades as a mob boss while Gray Hulk dons a pin-stripe suit, becoming Mr. Fixit.