Diane goes into labor unexpectedly and when no one can find Billy she reluctantly asks Kate to be her coach. Wilkes must get a family to safety from an abusive husband/father. McNeil and Catera take dance lessons (with special guest star Kenny Ortega, who choreographed ""Brain Salad Surgery."" Billy arrives at the hospital and discovers that Diane is having a c-section after her and the baby have gone into distress during the labor.

Kate discovers that a patient is using Viagra to cheat on his wife; Jack gives a blood transfusion even though it's against the patient's Jehovah's Witness religion; a musician fears his creativity may be stifled by the medicine Aaron prescribes for his bipolar disorder; Joe's son drives the staff crazy as he roams the hospital behaving exactly like his father.

McNeil performs a hand transplant on the patient, and uses the patient's dead mother's hand. Kate is accepted by NASA. An old childhood friends visits Watters and asks for one of his kidneys.

Dr. Alberghetti performs a surgery with another surgeon, who is in Sri Lanka.

Rumors fly that the hospital is about to be sold again; a man seriously injured in an accident wants to be the guinea pig for the computer program he's invented that can help him move again.