Austin and NcNeil fly to London for a conference and are forced to perform lifesaving surgery with only an airline medical kit. Shutt begins his psychiatric residency.

Shutt has his first group counseling session with a family, and tries to help a young man whose brother commited suicide. Wilkes father comes back into his life. Hancock and McNeil try to treat a boy whom he suspects is abused, even though the child and his father deny the abuse.

A family eats poisonous mushrooms and the mother and two sons must receive a liver transplant. A donor is found for the mother and the father is a match for the two sons. The father decides to have a live donor transplant, but is told by Kronk that only one of his children can receive the organ. Austin and Cacaci have to attend a sensitivity seminar, which only makes Austin worse. With Shutt's help a patient remembers a sexual abuse that happened during childhood, but the parent vehemently deny it ever happening. Drs. Grad and Kronk get kicked out of lamaze class.

After the mysterious death of a seemingly healthy 15 year-old Dr. Wilkes decides to investigate. A lesbian wants her lover to die with dignity and fights her family to get her wishes.

A famous artist has an inoperable brain tumor. She convinces Dr. Shutt to run away to California with her.

Dr. Kronk's mother visits. Aaron spends time with Samara in California. A woman offers Dr. Hancock money to sterilize some of his patients.