Frankie takes on the system to save a patient, and lands in trouble. Lou finds out it’s not always wise to have an affair with a boss; and Tabb questions his ability as a doctor.

When a heart transplant patient dies, Frankie fears the surgeons will close ranks to cover up a medical error. Lou realises she and best friend Frankie may be on different sides.

When a patient wants to turn off the device keeping her alive, Steele tries to dissuade her. Lou feels betrayed when Frankie takes on a Root Cause Analysis into a patient’s death, threatening her job.

Chad Berger's days as a doctor are coming to an end, but he is determined to see through a complex set of paired kidney exchange transplants. Will he be able to do so, or will his own condition get to him?