Jess and the Most Wanted team head to Tennessee to track down an undercover DEA agent who appears to have turned dirty amid a major drug ring operation. Also, Sarah wonders if it was a mistake to move in with Jess and Tali so soon.

The team's new leader, charming but formidable Special Agent Remy Scott, takes charge as they investigate a series of homicides tied to a forbidden love between a young teen and her older boyfriend.

Rookie agent Ray Cannon joins the Fugitive Task Force as they hunt down a mysterious killer targeting IRS offices.

The witness Remy and Kristen are visiting in prison is put in danger when a riot breaks out, leaving the staff and visitors held hostage by two murderous gangs.

The team helps Remy try to catch his brother’s real killer 25 years after Mikey was murdered.

When a mysterious deal goes south, leaving behind multiple bodies, the Fugitive Task Force heads to Virginia to put the pieces together with the help of a familiar face and new addition to the team, Special Agent Nina Chase.

The Fugitive Task Force springs into action after four detectives are shot dead during a prisoner exchange outside of a diner in New Jersey. Meanwhile, Remy struggles with having Corey as a roommate.

When a federal judge and his wife are shot dead in New York, the Fugitive Task Force goes on the hunt and finds a connection to a man who is hours away from being executed in Missouri. Meanwhile, Remy and Hana both grapple with being single and living alone.

The Fugitive Task Force races to catch the culprit threatening Manhattan with a dirty bomb. Meanwhile, Ray prepares to celebrate a major life milestone as his wedding to Cora approaches.