McCall races to find a woman kidnapped by a serial killer whose past crimes went undetected because the victims were from marginalized communities. Also, trouble arises for McCall when her vigilante activity puts her on Manhattan District Attorney Avery Grafton's radar.

McCall and Mel work with a jaded ex-cop to find the killers of a beloved Chinese American restaurant owner, who was the victim of a hate crime masked to look like an accidental electrical fire.

When a Venezuelan migrant is accused of murdering a prominent congresswoman whom he and his wife were staying with, McCall and the team work to uncover whether or not he was involved. Aunt Vi tries to look after a student who seems to be experiencing distress at home.

When Fisk tasks McCall with tracking down an ex-MI6 agent in Paris with whom she had a past relationship, she must convince him to help her track down a crucial document that his friend was hiding. Also, Delilah faces discrimination at her new fashion internship.