McCall endeavors to help an escaped prisoner wrongly accused of murder who is too distrustful of the justice system that failed him to accept her aid. Also, McCall worries when her daughter, Delilah, stops hanging out with a close friend, and Detective Dante's search for McCall takes an unexpected turn.

McCall races to find a woman kidnapped by a serial killer whose past crimes went undetected because the victims were from marginalized communities. Also, trouble arises for McCall when her vigilante activity puts her on Manhattan District Attorney Avery Grafton's radar.

McCall races to help a concerned wife locate her husband before he helps an extremist group carry out an imminent bombing in the city. Also, McCall worries that her anonymity will be compromised when Delilah asks her to participate in a mother/daughter social media video.

McCall is hired by a concerned mother who suspects her teen son has joined a local gang, leading McCall to the boy’s surprising motivation behind his spiraling behavior. Also, Delilah faces anxiety as she prepares to speak at her friend Jason’s memorial service, and Dante worries when the new detective pursuing McCall sets his sights on unmasking the people closest to her.

McCall comes closer than ever to being captured when she races to prevent the murder of District Attorney Grafton, the prosecutor seeking to bring her to justice

Mel’s past military expertise proves critical when McCall is hired by District Attorney Grafton to find a sniper on a killing spree, seemingly selecting victims at random. Also, Delilah experiences PTSD when the sniper shootings cause her to relive the trauma of her friend’s fatal shooting.

McCall races to find Dante when he’s abducted by a pair of panicked deputies who fear reprisal, after they detained Dante without cause and used excessive force before realizing he’s a fellow cop. Alone and injured, Dante experiences hallucinations that reveal his complicated childhood.

When Aunt Vi is the lone juror on a murder trial who believes the defendant is innocent, McCall covertly investigates the case to find proof that Vi's instincts are correct.

McCall’s determination to apprehend Mason Quinn, the criminal responsible for Bishop’s death, veers into a dangerous obsession that could cost her everything. Also, Delilah finally meets her mother’s vigilante team when she requires Harry and Mel’s help to prove a fellow classmate made her best friend a victim of revenge porn. Second season finale.

When the mother of a patient dying of a rare brain disease holds a hospital hostage in an attempt to get her daughter a lifesaving surgery, McCall races to resolve the situation peacefully while dealing with pushback from government forces.