Kimmy and Dora (both Eugene Domingo) are identical twins but are as different as night and day. Kimmy is the smart, dictatorial type while Dora is the slow, dumb-wit sister. Kimmy has always been jealous of her sister as Johnson (Dingdong Dantes), the man she really likes, only has eyes for Dora. All hell breaks loose when their father(Ariel Ureta) gets a heart attack and makes Dora the majority owner of their family business if in case he dies. Kimmy thinks this is unfair and gets the help of their lawyer Harry (Baron Geisler) to take care of "business". A misunderstanding brings forth a plan to kill Dora but they kidnap Kimmy instead. Now Kimmy must find a way to get away from her captors while Dora must act as her tough sister and control their corporation in order to hide the truth from their father.

The film will focus before the birth of the twins. It was a set-up arranged marriage for their father Don Luisito Go Dong Hae played by Ariel Ureta to a lady with Korean Sang Kang Kang played by Alodia Gosiengfiao. Go Dong Hae refuses to marry and chose Kimmy and Dora's mother as his wife. In the present, an unexpected ghost is surfacing the family's lives and they found out that Sang Kang Kang that is supposed to be married by their father was already dead and they need to quest for the tranquility of their lives by travelling all the way to South Korea.[4] As Kimmy and Dora accepts the proposals of their boyfriends played by Zanjoe Marudo and Dingdong Dantes, strange things began to happen leading their boyfriends and their father in a comatose condition. Sang Kang Kang is back for revenge, and Kimmy and Dora are trying every possible solution to fight against the revenge ghost.

The film is set before the events of Kimmy Dora: Kambal sa Kiyeme wherein the twins are seen disputing the ownership of the family corporation. The film was inspired by the James Bond film series in terms of musical score and visual effects.