When his former secretary is accused of a murder, Perry Mason gives up a judgeship to defend her.

A priest is murdered and the main suspect is a nun.

An actor rigs a fake shooting on TV with the connivance of his friend, the show's host, but the practical joke goes wrong when the gun turns out to contain a live round.

Perry must defend the husband of an old flame from a murder charge.

Jordan White, a publisher friend of Perry, is called to a hotel where a guest, famous horror writer David Hall, has cleared out the hotel for a weekend and has called his "friends" - an actress, a fortune-teller, David's private assistant and the two remaining staff at the hotel to discuss business. They have come to the hotel as all of them are going to sue David over his new book - "The Resort" which characters are obviously based on Jordan and the guests. A practical joker, David plays tricks on them until he is thrown from the high tower of the hotel where Susan Warrenfield, the manager and owner of the hotel sees the fall and then Jordan at the tower causing the police to arrest Jordan. While Perry and Della try to solve the main mystery, Paul tries to find out who is trying to scare Susan away from the hotel. Could it really be a ghost or a more earthy visitor?

Perry investigates the murder of a former madam and uncovers a multimillion dollar banking fraud in the process.

Perry is suing a gutter trash newspaper that is running a story about a love affair between him and Della. The editor also has "dirt" files on an Army General, his banker and other "clients". All of them make little-concealed verbal threats to him at a party but the person that hated him most is a female reporter who the editor had just fired from the paper for attempting to write a serious story. She threatens him and soon after the editor is found, floating in his pool, shot. The reporter is arrested for the crime and Perry, who has a personal stake in this matter, with the aid of Della and Paul set out to solve the mystery. But the other suspects just want the case over with and will go to any lengths to protect their pasts and their secrets

Mason defends a man he had sentenced to prison when he was an appellate-court judge. Now, 18 months after the sentencing, a new witness turns up to prove the man's innocence. Mason steps in to defend the man.

A woman suddenly disappears after an early morning walk, and her husband is accused of murder.

Ken Malansky, a law student of Perry Mason's, is accused of murdering a fellow student. Perry is reluctant to take on his case as the victim was the son of a close friend.

A young theatre director is accused of killing a more famous Broadway director. Perry takes his case.

A hockey player of friend of Ken Malansky's is accused of murdering a team owner. Perry takes the case.

The chief suspects in the murder of an author are the numerous colleagues whom he continuously plagiarized.

Perry Mason ventures to Paris to defend a U.S. Marine Corps Captain accused of murdering a man suspected of being a Nazi SS Officer.

Perry Mason defends the husband of a famous rock singer who was found being killed after having had a tremendous discussion with her husband and her manager.

A young woman from Las Vegas wants Perry Mason to defend her father.

Perry is at TV station "KGGY" to be interviewed but thanks to the interference of main anchor-person Brett Huston the interview is pulled. Mostly everybody hates Brett as Brett knows all the station workers secrets. He has also written a memo insulting all of the main station players - Vic St. John - the station manager, Twyla Cooper - the producer, Chuck Gilmore - the sports reporter, Gary Slate - the weatherman, Cassie Woodfield - the reporter and Gillian Pope. Brett is shot dead with Gillian's gun and therefore is arrested for the crime. Gillian calls in Perry, Della and Ken to investigate. As Della and Perry set out to solve the mystery, Ken gets close to Cassie but she is a suspect and when it appears that somebody is trying to kill her, the mystery deepens..

A gangster who has commited all kinds of crimes is accused to have killed his wife. As he was not the murderer in this case Perry Mason intents to find the killer...

David Katz is a world famous magician and he comes to Denver with his group to perform for a charity gala for disabled children. Also there is Perry and Della as all three are supporters of the charity. Kate Ford, an assistant with an arrogant attitude, tells David that she is, from now on, going to do an illusion in which an assistant is raised in a glass coffin only to disappear when the coffin is opened up in the air (while the assistant climbs out before the coffin is raised.) After a one night stand with David, Kate is pregnant and she blackmails David with this. David and his wife Judy can't have children so that comes as a double blow to them. However Kate, with her attitude, creates much hatred at her from the rest of the group. At the gala, the glass coffin is raised but when it opens Kate's dead body falls to the ground - strangled.

Della's friend is accused of murdering a rival fashion magazine editor.

A painter, believed to be dead, returns to make allegations that a gallery owner is selling counterfeits of his work. Later, the artist is murdered.

Sleazy talk show host Ted Mayne writes a tell-all book, which enrages and embarrasses several very prominent women. One of them, actress Roxanne Shield, loses her composure during an interview and winds up making a televised death threat. Of course, when Ted is murdered, she is arrested. Witnesses claim they saw Roxanne outside his apartment that night and police later find the murder weapon in her car. Renowned defence attorney Perry Mason accepts the challenge of defending her in court.

Perry Mason is invited to the marriage of the daughter of an old friend of his. But after the ceremony the uncle of the bride is dead. Certainly this is a case for Perry Mason.

The owner of a cosmetics company is unveiling a new cream which she claims she's been using. She's been keeping her age a secret and now reveals that she's 60 and owes her appearance to the cream. She's later killed and the formula missing. Her husband is arrested and Perry defends him.

Dr Sheila Carlin is good friends with Della who calls Perry in when she is being pestered by someone. On the theory that it could be somebody that she works with at a radio stations she arranges Perry to be interviewed by Winslow Keene who is also the station's owner. Winslow enrages the rest of the talk show hosts on the station by informing them of changes that he is making to their time slots. That night, Winslow is shot by a hit man hired by someone at the station and Sheila is set up for the murder. She calls in Perry and as usual Perry, Della and Ken swing into action to find out who really did it.

On the set of a popular daytime soap opera 'Mile High', actress Kris Buckner is being forced off by co-star Mark Stratton. When she says that she'll 'kill him before she leaves the show', she makes herself the prime suspect when Stratton is murdered by someone poisoning him. As an old friend, Perry Mason comes to the help of Kris and agrees to defend her. Meanwhile Ken goes in search of information with the help of fan of the show.

Anthony Caruso, an old friend of Perry Mason, comes to Denver on the request of Dee Morrison. She's married to famed photographer David Morrison, who wants to shoot a photo featuring his former models. The tricky thing is that all of his former models are also his former wives. But Dee knows Anthony can convince them to do it which he does. And David shoots them. Later Dee catches David it what appears to be in an inappropriate situation with his assistant. They have an argument and she leaves. Later David is found dead and she's arrested and Anthony defends her. And he suspects it could have been one of the wives

A former associate of Perry Mason returns to handle the defense of a world-class chess player accused of murdering a prominent TV personality.

The alleged suicide of a gubernatorial candidate triggers a series of mysterious deaths leading to the governor's mansion, and "Wild" Bill McKenzie, a friend of Perry Mason, is on the case.

Attorney Bill McKenzie takes the case when his niece is framed for the murder of a popular and demanding sitcom star.