After fleeing a police roadblock where he gets shot in the leg, Kimble hops on a truck headed toward Sacramento where he meets Sister Veronica (the nun whom he drove from Nevada to Sacramento in the 'Angels Travel on Lonely Roads' episodes) whom is now the principal of the St. Mary Magdalene School for girls. Kimble asks Sister Veronica to drive him to Tarlton, where the one-armed man supposedly works as a numbers runner for a local racketeer. But a 'bad-girl' student recognizes Kimble and calls the police, forcing Kimble to hide on the roof of a building despite his injury. Meanwhile, Sister Veronica (whom is suffering from a brain tumor) learns that another delinquent student has run away, and is torn between driving after the girl or staying to help Kimble.

While attending a minor league baseball game, Kimble unwittingly witnesses a man walk away with a woman whom is later revealed to be the daughter of newspaper publisher Andy Newark. After discovering that Kimble witnessed the proceedings, Newmark summons Kimble to his office where he tells him that the woman is his daughter and she has been kidnapped. Her abductors want a $200,000 ransom. When word leaks out, reporters surround the Newmark household and Kimble is unable to slip away. Meanwhile, the kidnappers, a former baseball player and a friend, realize that Kimble witnessed them. So, they plot to have Kimble deliver the ransom money so they can kill him.

Kimble becomes romantically involved with former recording star Gail Martin, unaware that she know his secret, and the $10,000 reward for his capture. Gail and her other lover, Alan Bartlet, are plotting to kill Alan's wealthy wife Norma, a former golf pro now confided to a wheelchair, and put the blame on Kimble so they can capture him and collect the reward money, and Norma's vast wealth.

Kimble is working at a cigar-making store owned by Jose Anza, and becomes close friends with his son Jimmy. Jimmy is caught between the expectations of his demanding father who wants him to play the violin and the harassment Jimmy receives from three street punks. When Kimble is shot in the leg after the police discover him, Jimmy hides the fugitive from both his father, and his uncle Miguel, a police officer determined to capture the fugitive.

Kimble travels to Washington D.C. to meet with a lawyer, named Frank Hobart, whom wrote a book titled 'Unjustly Convicted' which states that Kimble was convicted without the benefit of a fair trial due to the bias media circus influencing the judge and jury. Kimble wants Hobart to represent him while the lawyer tries to persuade the courts to re-open the Kimble murder case. Soon afterward, Kimble finds himself attending to Unawa, an African ambassador who suddenly collapses in the street. The grateful ambassador shelters Kimble at the African embassy, despite the protests from the ambassador's wife Davala. Kimble becomes aquainted with some of the embassy staff including the attractive Alison Preistley, whom belives Kimble's innocence as does Unawa. But only the skeptic Davala refuses to belive Kimble innocent pleads and calls the police. With the building surrounded by police led by Gerard, Kimble knows that they cannot enter the embassy because it is technically part of another coun

In the hills of Oregon, a young sculptor, named Andrea, hides Kimble from a local deputy, named Howe. But when the lawman finds him, Kimble retreats deeper into the mountains where he finds refuge in the home of John Mallory, a former scholar who cut himself off from civilization 14 years earlier and his only companions are two vicious German Shepherd dogs. Despite being aware that Kimble is a fugitive from the law, Mallory takes a liking to Kimble and forbids him to leave. Kimble is compelled to help the ailing Mallory as Deputy Howe closes in on their location.

In the continuation of this story Kimble and Gerard are on a train for his hometown in Indiana. And Kimble then reveals that the person who sent the bail money is his brother-in-law Leonard Taft. Kimble doesn't think it was him but someone from his hometown did send the money and used his brother-in-law's name. The one armed-man calls the Tafts demanding that they meet with him, someone does go to the meeting but it's not Leonard Taft but the one-armed man assumes that he is, and says that he remebers him. Obviously this was the man who sent the money and the one-armed man is demanding more money which he doesn't have. Kimble and Gerard arrive at the Taft residence and talk to Len, who tells them that someone called claiming the same thing and arranged a meeting, Kimble ans Gerard arrive at the place and find some bullets. But for Gerard there is nothing more that can be done; they then go back to the Taft house so that Kimble can say good-bye to his sister, and it's at that moment tha