Hungover Jasmine desperately tries to step up her game in order to win Ric over. Zosia refuses to emotionally engage with a terminally ill patient who reminds her of Arthur. Raf is positive about stepping up his career, but when a charismatic female patient comes in, he questions whether he should actually be spending more time living his life instead of putting work first.

Zosia's behaviour continues to spiral out of control leading Jac to become concerned for her. Morven faces her fears when she takes charge of a charming patient.

​Ric has been suspended and Tristan is on the prowl. An ever watchful Hanssen pays a heavy price when he takes Jasmine under his wing. When Ollie doubts a patient's credibility and questions Zosia's judgment, the ex-lovers clash. Determined to protect Zosia at any cost, Ollie is blown away by a startling revelation. Aware that she is subject of gossip and struggling to manage her feelings for Bernie, Serena is unprepared for what unfolds on AAU.

After saving a life in a near-death trauma case, an overconfident Morven clashes with Raf when he is not convinced that her motives are purely professionally.

When Tristan asks Guy for a personal favour, Zosia warns Guy that Tristan is not to be trusted. But Guy strikes a deal with Tristan and his reputation hangs in the balance.

When his living habits are called into question, a determined Dominic fights to prove his worth to Isaac but is unprepared for the consequences of his actions.

Part one of two. Guy's plans for his much anticipated Neurosurgical Unit are put in jeopardy when he makes a shocking discovery about Tristan Wood - the Unit's main benefactor. Meanwhile, Serena considers re-kindling her romance with a smitten Robbie but, with Bernie in her thoughts, can she commit to happy ever after with him? And Ric is pressurised to undermine everything he's worked for by Tristan.

Part two of two. A conflicted Guy fights to save Tristan's life, and Raf's budding relationship with Kim is tested when he makes a shocking discovery. Meanwhile, spurred by evidence of Essie's romantic conquests, Sacha tries online dating, but is it really a good match for him?

Dom stoops to low levels to land an assistant's position after Isaac gets a research grant. Elsewhere, Inga fights for her fiancé attention, and Bernie returns

Matteo's arrival irritates Jac and when the medic discovers his past misdemeanours, she throws down the gauntlet. Elsewhere, Dominic gets emotionally embroiled in a challenging case.

Jac puts her patient before her own health concerns, with serious consequences. Elsewhere Raf is taken aback when Parker is brought into hospital and is concerned about the boy's welfare.

When Kim gets positive news regarding her kidney treatment, Essie must deal with the imminent departure of Parker, who has been staying with her. Ollie is devastated when Matteo reveals he plans to ask Zosia out. Morven struggles to master her role as teacher, particularly with the unruly Cameron.

A terrifying blast from the past upsets Dom's plans for the perfect Christmas with Isaac, while Jac pushes her closest friend away as she waits on some Life changing news.

Mo strives to suppress her true feelings for Mr T, Jasmine is given her last chance on the Acute Assessment Unit, while Essie and Raf comes to blows after a difficult patient.

When Mo uncovers a secret, Mr T and Inga's Swedish-Style wedding takes a dark turn, While Serena, Elinor and Jason are involved in a car accident.

Oliver must compete for both funding and Jac's support when Matteo pitches a tempting rival project, and Dominic tries to keep his relationship with Isaac a secret from his parents.

Sacha becomes suspicious about Essie and Raf's relationship, and Fletch fights to save his friend Artem's life when the old gambler returns to the Acute Assessment Unit (AAU)

Mo returns from maternity leave and drops a bombshell, while Dominic gets a shock when he realises that going to Hawaii with Isaac is not going to be as straightforward as he hoped.

A grief-striker Derena returns to work looking for answers and Dominic is in turmoil when Isaac reveals a devastating betrayal. Meanwhile, Ollie and Zosia question if they are ready for the next stage in their relationships.

A familiar face makes a return under shocking circumstances, and grief-stricken Serena takes an eager Jasmine under her wing, but both get more than they bargained for.

Jac may finally acknowledge her feelings for Matteo, and Bernie sees through Serena's attempts to keep everything normal. Meanwhile, Raf is determined to remain professional when Kim reached out for help.

Isaac's dark side comes to surface as his relationship with Dom reaches breaking point, and Serena's mentoring of Jasmine gives Morven cause for concern.

Raf enthusiastically makes plans for the future with Kim and the twins he is to be a father of. However, his hopes and dreams looks set to be dashed by a series of revelations.

Jasmine fights chronic fatigue while trying to impress Serena, Essie wants to become Parker's foster mother, and Oliver tries to maintain his new zen outlook when rivals Jac and Matteo receive project funding.

Dominic's trust in Issac is rocked when a patient they both know is abandoned at the hospital having overdosed, and Fletch makes a shocking discovery about the man Morven has been messaging.

Essie is shocked when Parker turns up with a friend, while Zosia is harbouring a secret from Ollie and is horrified to learn that Isaac knows what it is.

Isaac lashes out when Dom questions their relationship, Serena is dealt a further blow after Elinor's death, and a drunken mistake prompts Ollie to take a big step in his relationship with Zosia.

Serena faces her demons and comes to a heart-wrenching conclusion, Zosia takes action when Issac reveals his true colours, and Mo risks her professional reputation.

Dominic and Isaac's toxic relationship finally reaches boiling point, Fletch's world is shattered by a life-changing revelation, while Matteo tries to reunite Jac and Jasmine.

Jac and Matteo's relationship seem to be heading in the right direction, but when she becomes suspicious of his motives, her investigation unearth skeletons in his closet.

Matteo and Jac clash over the patient, Sacha Tries to keep a secret from Essie, and Ric cracks the whip on the Acute Assessment Unit Floor, But a surprise visitor throws him off his game

Mo finds herself caught between pregnant patient Trixie and Derwoods mother, Oliver's eagerness to impress causes friction between Bernie and Ric, While Sacha revisits his own childhood when his first girlfriend is admitted.

Matteo wants to prove his marriage is over, but a face from the past brings up painful memories of his life before Holby, Meanwhile, Dominic struggles with his first day back.

Jac's job and livelihood are at risk when a mystery patient arrives on Darwin and seeks help, while Keller welcomes a new face to the team. Elsewhere, Oliver has his mind preoccupied with a surprise from Zosia.

Lofty is unexpectedly confronted with his past and realises that he has to come to terms with the life changing choices he has made, while Mo is ecstatic to be offered Jac's job.

As a personal emergency strikes, Mo Makes a heart-wrenching decision, and when Nina oversteps the mark with a patient on AAU, her judgement is called into question.

Dominic and Sacha clash professionally, and with Jac and Jasmine at odds, Fran makes it her business to reunite them - with unsettling consequences,

Meanwhile a new arrival on Darwin gets more than they bargained for.

It's crunch time for Mo, who has some difficult life choices to make, and a patient who is dear to Ric forces him to try to mend broken ties. Meanwhile Jasmine has growing suspicious of Fran's intensions with Jac.

As Jasmine begins to investigate the past, She makes a shocking discovery, while a misunderstanding leaves a vulnerable Dom at odds with his new friend Lofty.

Jac buries herself in work, determined to save he life of a scared patient, while Sacha is forced to confront his faith when his mother sets him up on a blind date.

Plus, Donna returns

A grieving Morven will not accept the circumstances of a close tragedy, while a familiar face arrives on Keller for emergency surgery, putting Sacha in a compromising position.

Jac and Fran get the shock of their lives when someone from their past turns up at the hospital while Raf realises that he likes Essie more than he's letting on.

Essie worries that she is not being a good foster parent to Parker, and a tricky patient diagnosis throws Morven straight in at the deep end on her first day back.

Donna is dealt a cruel blow by her ex, but assistance is on hand from a surprising source. Elsewhere Dominic wants to uncover the truth about Lofty's life, but he is not ready for what unfolds.

Nina strikes a deal with a face from her past, party animal Morven makes a regretful decision, and Sacha struggles with the new woman in his life.

Bernie is confronted with an impossible situation, Ollie and Zosia are made an offer they cannot refuse, and Lofty has fallen out of favour with Dom.

Guy requests Oliver's help with a patient, hoping to foster support for a new research proposal, Sacha's rabbi is taken seriously ill. Nina questions Matteo's feelings for her.

Oliver struggles with the thought that Tara's death could of been prevented, while Zosia is offered a chance to advance her career. Meanwhile, Lofty worries Dom still has feelings for him.

When events take a tragic turn during the Holby Half Marathon, Lofty is forced to finally confront his feelings for Dom and Fletch must enlist Jac's help to treat a patient.

Hanssen is forced to confront his past when a familiar face arrives as a registrar, and Zosia finally relaxes into some wedding planning, but Guy's behaviour sparks fresh concern.

As Guy's behaviour becomes increasingly erratic, Zosia's concerns put her in an impossible position, and Donna is shocked when her patient has a surprising visitor.

It is the day of Oliver and Zosia's wedding, and as the family and friends gather, the arrival of a particular guest threatens to ruin their happy day.

In the aftermath of the wedding, Zosia has a hard decision to make, while Dom and Lofty are in an awkward situation when Dom's boyfriend turns up on Keller.

Matteo makes a stranger recognise Nina on the ward, and Fredrik tries to impress Hanssen, but only winds up testing his patience.

Fletch must deliver some bad news as the reality of being Director of Nursing set in, and the arrival of a familiar face leaves Essie contemplating an emotional farewell.

Fredrick and Sara need to convince Hanssen to give them his professional backing, and an impromptu visit from a loved one gives Raf food for thought. Oliver and Matteo go head to head to win over Damon.

Nina must decide if she can trust Fredrick when he discovers a secret that forces her to question her future with Matteo, and Oliver is haunted by a face from the past.

On the day of Ric's coroner's court hearing, Donna discovers contradictory evidence that threatens his defence, and Dom struggles to find reasons to find a research subject.

Hanssen finds an enexpected ally in Sacha as he battles to ensure Holby'survival, and an unwanted visitor compounds Donna's problems when she returns to work.

Oliver is determined to win funding for his chest wall rec0nstruction project, and Morven is faced with a shock from her past when she discovers the identity of Lofty's mystery patient.

With the merger decision hanging over the hospital, Fredrik had his own future at Holby firmly on his mind, and Donna's friendship with Rik takes an unexpected turn.

In light of Nina's news, Matteo can no longer run from their past, and Jac faces mounting pressures, both personal and professional. Meanwhile, an unwelcome visitor puts Donna in a tough position.

A new face arrival in Holby sets the wheels of a change in motion, Jac is forced to assess her personal and professional lives, and Raf is reminded of why he fell in love with medicine.

t remains to be seen how the staff will cope when a face from the past arrives with a chilling vendetta.

Dominic is determined to push new F1 Meena to the limit. With the hospital still recovering, Hanssen takes position at the front line on AAU.

An overworked Morven finds herself torn between her past and her future on Christmas Eve. Essie is surprised to bond with Gaskell over an unusual patient.

Jac, Ric and Sacha face off against old rivals while pitching for a million-pound prize fund. But as the competition threatens to divide the group, should they be more worried about their friends than their enemies?

Serena's new year is once again marked by tragedy when a loved one is brought in for emergency surgery. Dare Serena put her personal feelings aside and perform the operation to prevent history repeating itself?

A surprise blast from the distant past returns to run a Young Adult Unit alongside top consultant Ange Godard. He successfully puts everyone on tenterhooks with his notorious barbs and quips, until things take a surprising turn, much to everyone's surprise.

Nicky competes with Cameron for the junior doctor lead position only to realise that high accolades aren't everything when it to come to surgery.

Serena steps in to protect her ward when an old face from the past turns up and offends them. Serena fails to see the funny side and takes control.

Ange finally allows Dominic the chance to work on her new unit, after much persistence, but she isn't sure whether he has the chops to be a great doctor. When Dominic is economical with the truth, Ange has to confront him and then feels that he's not trustworthy.

Nicky and Cameron find common ground when they have to work alongside an unforgiving Jac. Struggling to prove that he's worthy, Cameron goes all out to impress her. When things go wrong, will Cameron be forced to confront his own mistakes?

Ric's former wife Lola returns to Holby to work alongside her former flame on AAU. Serena and Zav are highly amused by the tension between them, but Ric soon realises that he actually has residual feelings for his ex. But are they reciprocated?

Frieda is happy her life is on an even keel, but her contentment is shattered when her ex-boyfriend Roman unexpectedly reappears. Can a wary Frieda open her heart and dare to imagine a future she had thought was gone for good?

With their relationship going well, Xavier is keen to step up and ease the burdens weighing on a stressed Donna. But all does not entirely go to plan when Zav embarks on some impromptu parenting of Mia.

Ange feels the pressure as she works to sell her vision for her Young Adult Unit while treating a difficult and vulnerable patient. But striving to be all things to all people, Ange fails to get to grips with the behaviour of a returning colleague who might really need help.

When Holby is overwhelmed by a winter crisis, Ric goes above and beyond to treat his patients. But as the pressure reaches fever pitch, can he continue to accept Holby surviving on nothing more than good will and the occasional miracle?

To Jac and Fletch's concern, a grief-stricken Frieda immerses herself completely in work, but when she's challenged by a patient's confrontational father, and with her emotions running high, Frieda embarks on a fight she has to win.

When Ange has her work cut out on YAU thanks to an obstinate teenager, it's down to Essie to persuade an unwilling Ange to enlist help from a source who's a bit too close to home.

When a family secret is exposed, the dispute causes a young patient to delay vital surgery, but fearing the consequences of such a decision, a concerned Ange must find a way to make her reconsider.

Keen to highlight the constant pressures Holby faces on a daily basis, Ric enlists the help of an influential acquaintance. But when an innocent patient is caught up in his personal crusade will Ric do the right thing?

When the opportunity to attend an overseas conference arises, Nicky and Cameron must battle it out, but with Nicky running on empty does she have the strength to come out on top?

While Holly's condition weighs heavily on an emotionally invested Ange, Holly's distraught parents must put their differences aside to make a heartbreaking decision, but are they prepared for what lies ahead?

When new locum Chloe covers on Darwin, a smitten Cameron sets out to impress, but with a tricky patient keeping him on his toes will Cameron step up to the plate?

There's no love lost between Xavier and Carole, so when a disgruntled Xavier is tasked with treating spiritual Carole, it's clear she's not the only one in pain.

Zosia arrives at Holby keen to get back working on Darwin. With her knack for irritating Jac in full swing, will Jac be able to track down Frieda before Zosia gets too comfortable?

Ange struggles with Holly's parents who are intent on fighting for their daughter. When an offer of hope for radical treatment comes from America, Ange does her best to make them see what is really best for their daughter.

Donna and Xavier struggle to keep their domestic arguments at home - will being forced to work closely together for the day sort out their differences or drive them further apart?

Zosia's big news gets a mixed response, and Jac remains suspicious about her real reasons for returning to Holby. Zosia's situation is further complicated when a handsome American turns up wanting to tempt her back across the Atlantic.

Sasha is rattled and embarrassed when an old flame appears on the ward with their ill partner. Following diagnosis, Sasha gets to try out his new transplant procedure and by the end of the day has two reasons to celebrate.

Following an incident with protestors, Jason refuses to leave Hanssen's office until his demands are met. Despite Serena’s pleading, he stands firm and eventually a difficult decision is made about a long-term patient, much to Ange’s annoyance.

A computer virus shuts down Holby’s power, putting Jac and Connie at loggerheads as they fight against all odds and in makeshift conditions to save the lives of close friends and colleagues.

During a hospital-wide evacuation, Ric mounts a daring rescue for a trapped and weakening Essie – even as he struggles with a shocking revelation about Darla.

In the midst of chaos, can Ange and Serena agree on how best to care for Holly, who continues on life-support?

A desperate Ange pleads with Holly’s family to see reason, but when the ruling comes back, the anger finally boils over with devastating consequences for Fletch. Ric's son Kofi arrives at Holby wanting to find out what’s going on with Darla. Struggling to keep his granddaughter's pregnancy a secret, Ric battles to keep his family together and do what’s right for everyone. An excited Zosia looks forward to working with Frieda, only she doesn’t get the reception she was expecting. As the pair team up to tackle a case, Zosia does her best to win over Frieda, with hilarious results.

As the protesters grow angrier Holby tightens security, Fletch realises there may be darker forces at play with Theo’s disappearance. Chloe struggles to decide if staying at Holby is the right thing to do. Dom tries to persuade her, but is thrown off by a surprise visitor. A romantic evening doesn’t go as planned for Xavier and Donna when his mother arrives, putting Donna in a difficult position.

Ange follows a hunch and ends up uncovering a shocking and long buried secret – one with the potential to tear her life completely apart.

A downbeat Frieda faces tough choices when an old friend of Roman’s appears in Holby in desperate need of help. Can she manage to work within the system and play by the rules?

Cameron and Xavier are forced together on Darwin, where Xavier appears to take delight in Cameron’s dating woes.

Chloe is surprised and immediately wrongfooted when ex-boyfriend Evan unexpectedly turns up on Darwin Ward. Is it possible he’s simply there to care for his sister Phoebe?

As Ange reels from her recent earth-shattering discovery and tries to plan her next move, Carole unexpectedly confronts Dominic with painful and long-buried secrets from his past.

In the midst of a chaotic shift, Donna is surprised by Mia’s unexpected appearance – forcing Donna to navigate some sensitive parenting territory.

A bewildered Dom struggles to come to terms with a shocking family secret and he immerses himself in work. However being around Ange

proves difficult, causing Dom to make a drastic decision about his career. Will Ange convince Dom to change his mind? Donna will do anything to protect her daughter, but when she oversteps the line in a well-meaning attempt to shield Mia, Donna’s parenting is called into question. Though Serena offers some sound advice, can Donna accept Mia is growing up?

An enthusiastic Zosia is keen to take on more challenging cases but Jac, still privately resentful towards Zosia, sidelines her. Feeling disgruntled, Zosia undermines Jac’s authority, but it only adds strain to their already fraught relationship.

A startling incident forces Zosia to reconsider her future at Holby, Cameron has to treat a close relative of Xavier's, and Dom tries to keep Carole at arm's length.

Jac’s top-dog status is challenged when a talented new surgeon starts at Holby and instantly causes a stir. Dom is irritated when Carole starts work on reception, and Ange tries to limit family fallout. Donna is flattered to be offered a new career opportunity, but does she really want the extra responsibility?

Kian’s big personality and alternative methods are beginning to grate on Jac, but is it just a case of professional jealousy? Fletch reminds her that she’s only as good as her team and should allow him to thrive. Dom tells Ange he wants to be a proper part of her and Chloe’s lives. In response Ange finally opens up to Dom, revealing a big family secret. When Sue makes a big mistake on her first day at the new job, Donna covers it up. However being the favourite of the new boss poses new challenges.

Ange plans to tell Chloe her biggest secret, but a surprise locum throws her day into disarray. Ric’s granddaughter, Darla, arrives at Holby, forcing Ric to deal with her pregnancy head on. Kian rallies Nicky and Cameron to help him find out who Jac’s mystery patient is.

As Chloe tries to come to terms with the news that Dominic is her half-brother, she’s forced to operate with him and Ange. But as tension boils over and Evan helps her uncover a home truth, will Chloe be able to cope?

Lofty returns to Holby after the holiday of a lifetime. With something clearly on his mind, he wants to speak to Dominic but misses his moment when he learns that Ange is Dominic’s birth mother. But what is Lofty hiding, and who is just around the corner?

When an infestation of rodents takes refuge at Sacha’s home, he decides it’s time to move out of Jac’s house and leave her in peace. Jac worries whether he’s really ready, but what will Sacha do to convince her?

Dominic faces his difficult past when he goes head to head with his abusive ex, Isaac. Ange and Carole band together in order to cope with the fact that Isaac has returned, affecting Dominic’s life. Jac’s conscience is thrown into conflict when she meets a previous patient who has something she wants. How far will she go for personal gain?

Will Lofty and Dom’s marriage survive under the pressure of Isaac’s presence at Holby, and is Sacha’s relationship with Patricia over before it’s even begun?

As Dom and Isaac grow closer, is Dom at risk of falling under his spell? Hanssen finds himself in unfamiliar territory when an estranged relative arrives at Holby, and Chloe gets an unpleasant surprise when she returns to work.

The manipulative Isaac continues to drive a wedge between Dom and Lofty, but when Isaac puts Lofty in harm’s way and the net is closing in, is Isaac’s fate sealed?

Good intentions backfire for Cameron when an intervention doesn’t go his way, but when faced with an opportunity to protect Chloe, Cameron makes a selfless gesture.

Hanssen must navigate the world of parenting to figure out what’s troubling his unusually quiet grandson Oskar.

When Xavier’s mum arrives on AAU talking in riddles, Donna does her best to shelter him from her behaviour - but will he appreciate the intervention? Sacha makes a romantic gesture but finds something unexpected in Patricia’s cleaning cupboard. Nicky turns her nose up at working with Jac, who ensures she’ll live to regret it.

Xavier tries to build bridges with Donna, but she’s having none of it. Cameron can’t quite shift his feelings of unease around Evan, and when he overhears a phone call his suspicions are confirmed. And Fletch is anxious about his first official date with Ange, especially when work threatens to get in the way.

Cameron tries to prove himself to Kian, but they clash over Kian's teaching methods. A frustrated Xavier gets relationship advice from the most unlikely source, and Carole opens up to Hanssen about her woes with Dominic and impending divorce.

Chloe’s day is thrown into chaos when Evan is attacked. With his life on the line, Evan asks Chloe a surprising question. Dominic is put under pressure when a surprise visitor arrives at Holby looking for Lofty. Wanting to keep his marriage intact, Dominic is forced to make a difficult decision. And after a night of partying together, Serena and Fleur Fanshawe are thrown together to help a patient on AAU.

As her loved ones continue to worry about her, Chloe learns more about Evan. Cameron wants to get out from under Bernie’s shadow, but he receives some devastating news. Hanssen learns that his grandson is not the only one who believes in the tooth fairy.

On the anniversary of a personal tragedy, Kian decides he must save a life today. Hanssen worries that with his family history he shouldn’t look after Oskar and wonders whether nature or nurture will have a greater effect on his grandson. Cameron struggles to accept some recent news and refuses help from Alex. When Serena tries to help him, she receives surprising news.

As the Holby team give a warm send off to a much beloved colleague, a surprising revelation sends Cameron into a spin. However, Cameron crosses the line when his drunken behaviour spills onto the ward.

Jac’s work-life balance is called into question when her ex’s new fiancee arrives at Holby with Emma in tow, and she’s forced to make a career changing decision. Will life on Darwin ever be the same? As Serena's tough façade slowly unravels, is grief finally catching up with her? And Dominic is on a mission to find out what Hanssen and Carole are secretly up to.

Is Chloe brave enough to tell Evan she wants a divorce? And what will he do if she does? Faced with choosing between work and his personal life, will Hanssen learn from past mistakes? And will having their therapist as a patient bring Dom and Lofty closer or push them further apart?

A distressed stranger turns up looking for Raf di Lucca. Will her secret change Essie’s life forever? Xav questions Ric’s competence, but is Ric’s outrage hiding a graver concern? Nicky learns to trust her instincts – and that includes suspicions about sinister Evan too.

Chloe's day is thrown into chaos when Evan's sister, Phoebe, returns to Holby. Essie is left torn when she is forced to make a difficult decision, and a high profile patient is admitted to AAU, but are things exactly as they seem?

Jac is rocked when Faye Morton returns to Holby bringing Joseph with her. Sacha struggles to do the right thing for a family grieving their mother.

A friendly face from the past gives Ric someone to confide in. Fletch goes on a mission that could cost him his relationship with Ange.

Fearing something may be wrong with him, Ric is absent when his granddaughter, Darla, goes into early labour. When Isla requires emergency surgery, Essie’s lie that she’s her adopted mother is in danger of being exposed. And as Chloe tries to move on from Evan, she has a feeling that he’s watching her.

Evan refuses to give up on Chloe and proves what a real threat he can be. Cameron abandons his quest to help Ric when he receives heart-breaking news.

Will it be Chloe or Evan’s version of events that will be believed? How can a grieving Cameron make amends for failing Chloe when she needed him most? And what will an MRI scan reveal about Ric’s future?

Both Ric and Darla are faced with life-changing decisions, an aggressive stranger at the hospital threatens to blow Essie’s baby secret wide open, and will Kian be able to mend the heart of an old flame?

Essie is torn when Frankie returns wanting to take Isla home, Ric is caught between Serena and top neurosurgeon Max McGerry as they clash over his treatment options, and Jac returns from holiday and wastes no time in winding up a stressed Kian.

Max performs dangerous brain surgery on Ric, who must confront his own mortality. Dom is shocked when Helen returns to Holby and Lofty finds out she’s pregnant.

It’s Halloween and Cameron is haunted by his own ghosts. Jac receives a bombshell from Stacey, and will Dominic overstep the mark when it comes to Lofty’s baby?

In Holby City’s 1,000th episode, Jac is due to perform a milestone surgery, but will personal issues cloud her judgement? It’s Holby City Hospital’s 150th birthday and a familiar face returns for Fletch’s VIP celebration, but why are they really here? Ric is discharged from hospital, but is this the last Holby will ever see of the legendary surgeon?

As Elliot’s concern for Jac grows, will he ever be able to tell her his secret? Lofty is determined to be there for his new family, but will it be smooth sailing from here? Sacha is conflicted when his feelings for Essie resurface.

A heartbroken Lofty and Helen are rocked by tragic news which tears their world apart. A guilty Xavier evaluates his working relationship with Donna, and are the cards stacked against Jac at Darwin’s mortality and morbidity review?

Kian is desperate to deliver the surgery that Bea desires, but stressed Jac won’t play ball. How much will Kian sacrifice to give Bea what she wants? Dom and Lofty are too busy putting others first and not dealing with their own problems. Is their relationship strong enough to survive these tough times? Donna distracts herself by focusing on returning patient Cherie Grimes. But when fun-loving Cherie goes missing, will Donna be brave enough to convince them both to face their fears?

Elliot needs life-saving surgery. Jac is the only one qualified to do it, but will her struggles with anxiety result in her killing her mentor? Cameron sees an opportunity to make amends for past actions, but does so by manipulating a patient’s relative for his own ends. Still struggling with grief, Dom and Lofty are thrown when Carole returns from holiday blissfully unaware of their loss. Will she bring them together or only drive them further apart?

Jac has to face some home truths in the Psychiatric Unit when she's visited by the three wise men. Chloe gets some life-changing news that she has to share with Evan's sister, Phoebe. Xav and Cameron battle to save the life of a young stab victim, but they soon discover that the girl isn't as innocent as she seems when her mother turns up.

On the day he and Dom are due to renew their wedding vows, Lofty finally makes a decision about what he really wants in life. A newly pregnant Chloe wrestles with her conscience, and Sacha attempts put himself first, which means he has to say no to hosting Christmas with Essie.

When Bea requires emergency surgery, a suspended Kian takes matters into his own hands, but at what cost? Essie’s feathers are ruffled by a flash new consultant, and how will Dominic react to an unwanted Christmas gift?

Confronted with an unwelcome patient, Serena is forced to make a life or death choice. Chloe decides she’s ready to move on in 2020, but will her decision hurt a good friend? And Ange and Fletch plan their first New Year’s Eve together, but will Sacha and Dominic’s interference scupper their plans?

Sahira is adamant that her father is innocent, Louis discovers Vicky is trapped in a toxic relationship, and Lucky isn't sure if Kian is really clean.

Dominic pushes Sacha to make an illicit choice, Kian and Chloe make a shocking discovery in theatre, and are the McGerrys at breaking point?

Louis is trapped as Vicky’s blackmailing escalates, a desperate Dom tries to convince Ange to take his case on, and Kian leads Lucky on a merry dance as he tries to dodge a drugs test.

Hanssen worries that the upcoming court case will cause more harm than good. Sacha prepares to risk everything for Dom, but is Ange onto them? Fletch tries to get to grips with his new job.

The cause of Reyhan’s death comes into question, putting Hanssen and Sahira’s relationship at breaking point. Dominic’s new found optimism might be too much too soon. Kian continues to lie to Lucky, but is she about to work out what’s really going on?

Donna leads the Holby nursing staff in a protest, but will Hanssen be moved by the nurses’ cause or are things about to get much worse for them? Lucky realises that Kian lied to her about where Andrei was staying, and an accidental encounter between Josh and Hanssen threatens to spill both their secrets.

When a majax strikes Holby – will self-harming Hanssen be heroic enough to ask for help? Secret addict Kian must choose between a young patient and Andrei – can he keep both safe? Thrust into the limelight, Jeong must diagnose a mystery condition – but will Dom help or hinder?

How far is wannabe consultant Dom willing to go to ensure his path to power? Burying her head in the sand over her BRCA1 diagnosis, can anyone get through to Max? Reeling from Andrei’s sacrifice, is Kian willing to betray Fletch's trust to get what he wants?

It’s the day of Max’s operation, and Ange and Josh’s relationship deepens. Kian convinces Andrei to return to the hospital to have his surgery, but is it enough to keep Andrei from leaving again?

Kian faces losing Andrei, just when he thought he had got him back. Dom gets a shock when a patient chooses Sacha as her consultant instead of him. Are Ange and Josh about to lose their jobs over their secret relationship?

Sparks fly between Kian and Fletch after Evie and Andrei disappear, Sacha and Dom compete for the top job, and Josh tries to win back Ange.

Defeated Josh questions his place on AAU, and will Fletch unravel when Darwin faces a crisis?

Lucky tries to overcome her personal crisis by throwing herself into work. A patient accuses Dominic of leaving an unwanted souvenir in his body during an operation. Kylie does her best to interpret Josh’s cryptic warnings over a potential faux pas with Louis.

Josh’s mum is not impressed that her 20-something son is dating a woman in her forties. The hospital faces an emergency inspection by the CQC, and is a patient lying to the Dom and Jeong about being bitten by a dog?

Dom’s mum Carole is admitted with a burnt arm, but is she hiding a more serious ailment? Kylie blurts out Ange’s secret to Josh, and Max tries to rally the troops after the disastrous CQC findings. To add to her woes, Sahira’s son turns up drunk, wounded and hiding a dark secret.

Dom is shocked when he discovers Carole’s secret, Hanssen is torn as to how to handle Abs’s secret, and can Josh prove to Ange that he’s up to the role of being a father?

Will Holby City’s new director of improvement be able to turn the hospital around? Can Ange put her personal news aside and prove that she runs a tight ship on AAU?

Hanssen tries to persuade Lucky to return to Holby, and a terminally ill patient advises Kylie to tell Louis how she really feels about him.

Holby’s new director of improvement is furious when Hanssen attempts to block their plans for AAU. Evie finds herself facing an impossible decision, and time is running out for Chloe to find a suitable candidate for Eli’s medical trial.

Evie struggles to cope as she is drawn deeper into Jeni’s world. Dom has doubts about mum Carole joining Darwin’s stent trial, and Kylie must overcome her issues with new nurse Mel for the sake of a desperate young patient.

Assisting in Eli’s experimental stent trial proves to be the hardest professional challenge of Chloe’s life. Can she overcome her fears? Donna’s teenage daughter Mia arrives drunk on the Holby doorstep after a party with Jeni’s dodgy clients, and as Carole’s dementia worsens, Jeong helps Dominic take her on an imaginary trip to the seaside.

Hanssen trawls hospital CCTV for a potential threat. As Carole’s dementia worsens, taking part in the experimental stent trial becomes increasingly risky. Aleysa, another of Jeni’s girls, is admitted with a suspicious cut on her arm.

Eli’s experimental stent trail looks like it will be over before it’s begun when his patient takes a turn for the worse. Ange prepares for the life-saving transfusion on her unborn baby, and Lucky uncovers the dark truth behind Jeni’s activities, but at what price?

Hanssen finds himself in a perilous situation. Will he be rescued in time? Kylie and Dom suspect an elderly patient may be in peril, and Louis fears for Kylie.

As Jeni starts making plans to send Evie away, will Fletch and Donna find out the dark truth about what she did to their daughters before it’s too late?

Jac refuses to listen to Max, who insists she starts looking into alternative treatment options for her tumour, and is new dad Josh really coping as well as Ange thinks he is?

Fletch confronts Jeni about what she did to Evie. With their latest round of IVF treatment scheduled for today, Amelia springs an awkward surprise on Eli. With Josh pushing himself at work and to be the perfect dad and partner to Ange, an unplanned visit from his mum Elaine leaves her worrying that he might be falling into old habits. What is Josh hiding?

Donna allows her personal life to affect her work and neglects Lucky. Jac and Josh try to win Holby a place on a cutting-edge therapy study. Kylie discovers that Louis and Mel are still together.

When Lucky wakes from surgery, Max has to deliver some life-changing news. Josh tries to cope with the pressures of fatherhood and work, and Henrik is shocked when a familiar face returns to Holby.

Lucky asks Max for an impossible favour. Hanssen reluctantly agrees to mentor a new protege, despite their shared and painful history. Will Ange notice that Josh isn’t handling the pressure before it is too late?

On Josh’s birthday, a surprise celebration causes him to fall back into dangerous habits. Kylie tries a bold strategy to save Lucky, and Russ and Hanssen find themselves locked in a store cupboard together.

Will Ollie be able to contain his deep-seated fears? Josh finds an unexpected reason to take the Green War of the Wards challenge seriously. Can Max and Kylie put aside their differences in order to save the planet?

Amelia must break some devastating news to husband Eli, Ollie's shady past threatens to catch up with him, and will anyone notice that forgotten and forsaken Jeong is in desperate need of a friend?

Lucky is readmitted to Holby, and Louis learns the truth about her suicidal thoughts. Jac falters just as she’s about to start the proton-beam therapy. Eli persuades Josh he needs to tell Ange about his bulimia.

Russ learns the truth about Ollie’s relationship with Maisie, while Max and Dom disagree over his diagnosis of a black female patient. Now that Ange knows the truth about Josh’s bulimia, will their relationship survive?

Eli struggles to focus on the ward as he worries about Amelia’s health. Russ tries to convince Hanssen that he is not irresponsible. Will Josh keep his word and attend therapy for his eating disorder?

Dom remains in denial about Carole's ailing health, Eli and Amelia face a difficult choice, and Ollie is eager to return to work, but Hanssen has doubts.

A young cancer patient returns to go under the knife on AAU, Amelia struggles to cope with yet another devastating setback, and Kylie makes a mortifying Secret Santa faux pas.

Facing a visit from the regulatory body, Jac hopes a complex operation will show Holby at its best. During a surprise inspection, a patient comes into AAU with a suspicious motorbike injury. And can Hanssen and Russ persuade a reluctant patient to accept a lifesaving liver transplant?

Dom returns from compassionate leave, but Sacha is concerned he isn’t ready. Jac may be prioritising Holby over her own health - is Fletch’s faith in her misplaced?

Eli is compromised when Jac implores him to perform risky surgery on her. Fetch finds himself seriously considering Regina's job offer.

As Fletch’s faith in Holby is dented, a job offer from St James’ becomes increasingly appealing. Hanssen discovers Billie’s secret and is reluctant to keep it from her father. Nicky reaches breaking point with Juliet, but is turning to Amelia for support the answer?

Jac pushes Nicky to overcome her demons and become the doctor she knows she can be. But just how far is Nicky willing to go? Donna feels dejected when she gets no recognition from anyone.

Jac’s ambitious plans for the hospital are pushing her staff near a breaking point. Donna struggles to balance it all. Will Madge keep her promise to spy for Regina?

Josh is tested when a familiar face is admitted to AAU. Max has her principles pushed to the limit. Eli wrestles with his conscience as Amelia presses him about Juliet’s future.

Nicky must find the strength to be a mother to Juliet or give away her baby for good. As the hospital is forced to lock down, Hanssen has to help deliver Billie's baby. As AAU handles the Darwin overflow, Ange notices Madge behaving suspiciously.

Kylie believes Madge is the victim of domestic abuse, Dom receives a lucrative offer from a private hospital, and Russ needs to proritise being a father to Billie.

It’s the moment of truth: will Holby finally get itself out of special measures? Meanwhile, Regina puts more pressure on Madge to betray Jac and the hospital.

Fletch makes a last-ditch attempt to find a surgeon to save Jac’s life. Kylie tries to persuade Jac to visit Madge at home to find out what is behind her betrayal of Holby.

The team operate on Jac to try to save her life, Josh's relationship with Claudia resurfaces, and Lexy receives good news about a new kidney.

As the reverberations of Jac’s surgery impact around Darwin and beyond, will life on Wyvern Wing ever be the same again?

Series Finale