Det är thanksgiving, och Clark, Lois och Jimmy beger sig till familjen Kents gård.

Lois och Clarks förhållande pressas till det yttersta när Superman utses till Metropolis mest eftertraktade ungkarl!

Superman, som är bortförd långt hemifrån, knyter an till sin kusin Kara. Dessutom får han veta sanningen om Krypton av de sista levande kryptonierna.

Lois and Jimmy confront Kara and make a plan to rescue Clark. Meanwhile, Brainiac delves into Superman's mind to figure out what makes him tick…and how to tear him apart!

Jimmy and Kara race back to Metropolis to stop Brainiac's invasion of Earth! Meanwhile, Lois tries to free Clark from Brainiac's control, only to lose herself in an alternate reality where Superman never left Krypton…

Superman, Kara, Lois and Jimmy team up to fight Brainiac, but will Superman have to choose between saving Earth and saving the people he loves? It's truth, justice and a better way clashing with the might of Krypton!