Coulson and his team race to combat Hive's control over the Inhumans, as their enemy's deadly plan for the human race is revealed.

Daisy has left S.H.I.E.L.D. and is trying to solve the mystery of a bunch of serial killings in the Los Angeles area. At the same time her old friends suspect her for the killings and are following her trail in an attempt to find her.

Daisy goes to battle Ghost Rider at a terrible cost, and Coulson faces the new Director, and his bold agenda surprises them all.

Suspicion turns to paranoia when the team doesn't know who can be trusted as more LMDs infiltrate S.H.I.E.L.D.

The clock is ticking for Daisy and Simmons to get the team out of the Framework, but not everyone is ready and willing to leave.

Coulson and the team's victory in the Framework is short-lived, as an even deadlier enemy looms against them all.

Coulson and the team set out to rewrite the course of humanity's fate; they're unaware that their efforts will dramatically change one S.H.I.E.L.D. agent's life.

As Fitz and Simmons race to find a way to seal the Rift, they are faced with one of their greatest fears manifested.

While an agent's life hangs in the balance, Fitz, Simmons, and Yo-Yo attempt to neutralize a weapon that could play a role in Earth’s destruction.

Coulson and the team find themselves under siege at the Lighthouse.

A newly determined Talbot takes Coulson to meet the enemy and attempts to avert Earth's destruction.

Coulson's life or death is the challenge the team finds themselves in, as the wrong decision will cause the Destruction of Earth.

Scattered across the galaxy, the team works to find their footing in the wake of losing Coulson.

It’s a wild night out on the planet of Kitson for the agents. While Leo and Enoch try their luck at the casino, nearby, Daisy and Simmons find themselves in a much... groovier situation.

Sarge has May; Atarah has Daisy, Enoch and Simmons; and now, there are two planets that need saving.

No time for the team to play catch-up, there's a planet to save.

The party’s over, and now the team must trust each other in order to face impending doom and an enemy that’s closer than they think.

Out of answers and running out of time, the agents must face the ghosts of their past in order to move forward.

With time running short, the team will have to go to hell and back to stop the end of everything.

With their backs against the wall and Nathaniel and Sibyl edging ever closer to eliminating S.H.I.E.L.D. from the history books, the agents must rely on their strengths to outsmart and outlast the Chronicoms. This is their most important fight, and it will take the help of friends and teammates, past and present, to survive.