The sheriff is under political pressure to find who killed an air marshall with a car bomb that the sheriff witnessed. Grissom, Catherine and Nick are pressured to produce results. Warrick and Sarah try to find the murderer of the wife of a singer who headlines on the strip.

The lone holdout on a jury is found dead in the jury room. The eleven jurors who were voting guilty and who hated the dead juror are the natural suspects. Nick reopens a four year old case when the sister of the victim comes forward with new evidence.

A mutilated female body is discovered tied to the undercarriage of a bus carrying prisoners from a women's correctional facility after a severed arm flies out from beneath the vehicle and strikes a car. Catherine leads the investigation and at first believes the woman was escaping, but the evidence increasingly points to murder. Back in town, Warrick probes the death of a gambler who was stabbed multiple times in his brother's kitchen.

Grissom, Catherine and Nick investigate the death of a runner during a competition. Meanwhile Sara and Warrick investigate the death of couple in a hotel room, initially thought to be a murder-suicide. Both cases take place during this 'cop' competition , with more than 20.000 attendants (all of them cops). This gives the investigations an interesting turn, as almost all the suspects and all dead people are cops.

A casino employee is beaten and raped on her way home from work, but she survives and identifies her attacker. Unfortunately, a DNA test sets him free and Grissom must wrestle with whether evidence can ever lie. Later, Grissom comes to the rescue of a coworker who ends up on the other side of the law

A wild night in Las Vegas has the CSIs simultaneously investigating four fatalities. Greg Sanders' first day in the field has him assisting Grissom's investigation of a fatal nightclub shooting. Meanwhile, Catherine probes into the death of a stripper found dead in a hotel room, while Sara and Nick look into the strange case of an "alien" body found near Area 51.

A woman is found dead in a hotel suite with symptoms of the ebola virus. Another woman is found dead with similar symptoms. Catherine and Nick investigate. Sara and Greg with help from Grissom try to determine how a the owner of a home was killed. His home was tented for infestation.

Grissom is confronted with new evidence while on the stand of a murder trial of a restaurant owner. This development requires the reopening of the case and Eckley initiates an inquiry into Grissom and his team. The results of the inquiry lead to dramatic changes of the CSI team and the series.

Grissom and his team investigate the starving death of a five year old boy. They discover the boy has siblings who are in danger too. Catherine and her team determine who killed a prisoner in a holding cell brawl.

Catherine, Nick, and Warrick investigate a badly mutilated body in the woods. The cause of death was a shotgun blast. Nearby is a beaver dam made in part with cash. Grissom, Sarah, and Nick try to determine how a man was killed in a hotel room. It leads them to a convention of big women.

Grissom, Sara, and Nick investigate a wildfire that killed one man and badly burned a woman. Catherine, Nick, and Warrick get the case of a family of three murdered in their home.

A man (Alan Rosenberg) whom Catherine flirted with at a bar reappears in her life as a suspect in a murder investigation.

Two amorous freshmen are found dead on a sleeping bag in a dorm room, and Sara and Greg run into one dead end after another as they try to determine why the students were killed. Warrick, Nick and Catherine figure out how a man is found dead in the center of a crop circle. Ecklie is called into duty for a man found dead in his car and his body later goes missing.

The two forensic teams come back together under the leadership of Grissom and Catherine just in time to tackle three separate investigations: a murdered couple found in bed in a suspicious trailer explosion; a beautiful stripper discovered dead and dumped in the worst part of town; and two bodies found baked and decomposed after spending five days in the trunk of a car exposed to the hot Vegas sun, forcing the CSIs to ""wrap"" up the evidence and bring it back to the lab for further analysis.

The team must investigate the death of a police officer who died during a shootout leaving hundreds of bullets on the crime scene. The case becomes complicated when it turns out that Sofia Curtis and Jim Brass were with the victims during the shootout. When it turns out the officer died from friendly fire, it is up to the team to find out who fired the fatal shot. Meanwhile, Sofia is wondering whether she fired the fatal shot or not. She decides to hide the fact that the officer stepped into her line of fire, afraid it will ruin her career.

The CSIs sift through the overwhelming evidence from a shootout with drug dealers in order to determine who is responsible for the death of a police officer killed during the incident.

A man accused of murdering his wife and co-workers leads the CSIs on a wild ride through a busy casino, eventually barricading himself and a hostage in a casino hotel room. The CSIs process the evidence from the crime scene to determine whether or not the man acted alone or had an accomplice. One of the CSIs eventually steps in as a hostage negotiator, putting himself in danger.

After several victims are found dead while performing normal, everyday activities, the CSIs must find the reason as to why each of the victims remain upright after dying.

The team investigates the death of a woman who turns out to be the daughter of a wanted criminal.

When the team discovers a connection between a new murder and a serial killer, Grissom secretly joins the class of a criminal pathologist (Laurence Fishburne) to help crack the case.

Langston and Nick are called to investigate a murder at a fast food restaurant and have quite a task ahead of them when they discover that much of the evidence is coated in cooking oil.

The CSI are called to three different crime scenes in one night that are seemingly unrelated, but each case's forensic evidence reveals a common link

When the CSIs are called to a murder scene at a familiar motel, Nick is thrown for a loop as he pieces together three separate murder investigations that all took place at the same establishment over the course of a year.

A series of indeterminate deaths test the deductive powers of the CSI team, who fear that a public health emergency may be in the offing. Meanwhile, a friendly rivalry over who will win an upcoming bikini contest takes a deadly turn...

When two seemingly different crimes turn out to be related, the CSIs discover they're interlocking parts of the same revenge plot.

The CSIs dig to find the truth about how a recent shootout at a gun store might connect to a young woman who may have committed suicide.

Catherine and Detective Vartann are thrown together in a hotel room for 24 hours as they stake out a duo making drugs in the room next door. Meanwhile, Nick and Langston work a case that involves a fetish which has become big business in Vegas.

The CSI's lives are on the line as they close in on the elusive Dr. Jekyll, and more than one member of the team may not live to see his capture, on part two of a two-part 10th season finale of CSI.

The CSI team investigates a well-orchestrated bombing at the funeral of Officer Franklin Clark

A vampire and werewolf convention becomes the center of a murder investigation.

The sky is falling or at least people are. The CSI's try to figure out if it was murder or sucide after a man is dead after falling from a hotel. Across town, a elderly woman falls through her table and her husband dead in the shower. The only two witnesses to the crime are an incooperative cat and a parrot who pleads the fifth.

The CSIs question the validity of an online picture depicting a murdered call girl until they find the same woman strangled to death in the dumpster that appears in the photo.

Jason McCann contacts Nick and says that he's in imminent danger. Langston has a courtroom war of nerves against serial killer Nate Haskell. A bomb tech disarms a bomb attached to Nick's house. But when he accompanies Nick, Catherine and Vartann to a warehouse with multiple booby-traps per square inch, Kip has to really earn his paycheck to find a safe way out for the CSI team.

While investigating the murder of a convicted ex-cop, the CSIs stumble upon a list in his prison cell with names of several individuals he believed might have been his wife's true killer.

The CSI crew is stumped when they discover a disembodied brain at a crime scene where all the other brains are accounted for.

Three new murders related to three unsolved (or incorrectly solved) crimes from the past come back to haunt the CSIs.

Catherine's friend Laura's mogul husband Mark has a lot to hide behind his successful international corporation, and he's hired a crack team of assassins to carry out the murders of anyone who might be aware of what he's doing, and that includes Laura's lawyer and Laura herself.

Russell seeks advice from a former colleague during an investigation into the death of a man's ex-girlfriend.

When a bomb kills an off-road race truck driver mid-race, the CSI team is called on the scene to investigate why.

The CSIs investigate the demise of a prominent news anchor during a live broadcast.