Two couples meet in a bar and one of the couples is murdered. When a second couple is murdered in a similar fashion the team suspects a pair of serial killers are on the loose. The case is complicated by leaks to the press and a judge reluctant to issue a warrant. Catherine gets some troubling news about her father's murder trial.

When the lead suspects in Grissom's serial killer case are murdered, Grissom suspects an inside job. Grissom and Brass are at odds when Grissom suggests it was a cop. Catherine and Sara investigate what happened to a college football fan when his bloated body is found in a bathtub.