Peter and Brian’s friendship becomes strained after Brian begins dating one of Meg’s high school teachers. Peter finds a replacement friend in James Woods, who is visiting Quahog because of a suggestion to rename James Woods High after Dr. Martin Luther King Jr.

James Woods returns to seek revenge against Peter. James Woods finds Peter's wallet, which he lost at Barry Manilow concert, and procedes to steal Peter's identity, and his family. Peter decides to ruin James' career and image.

Lois encourages Brian to submit his pilot script to a network. James Woods gets involved and things don't exactly go according to Brian's original plan. Meanwhile, Stewie has a bit of a mishap.

In this murder mystery special, The Griffins as well as all the other major characters become trapped in a mansion while they are killed off one by one.

When Peter decides to become a famous actor, he becomes Tom Tucker's agent as his first step toward stardom. Meanwhile, Chris dates a girl who looks disturbingly like a member of the Griffin household.

Family Guy takes viewers behind the scenes of a regular production week, with James Woods as the guide. See the ins-and-outs of what goes into the making of an episode and watch the drama unfold as Peter is replaced and ends up in the office of Fox Television Group Chairmen and CEOs Dana Walden and Gary Newman to pitch his very own new series.