When hunters gather together to celebrate the life and tragic death of one of their own, Sam, Dean, and Mary must take action when a demon starts picking off hunters one by one.

Lily Sunder steeps herself in black magic, honing her powers for over a century, waiting to exact revenge on a band of angels that murdered her family. Sam and Dean must work quickly to stop Castiel from becoming her next victim.

Alicia Banes calls Mary for help after her mother, Tasha, goes missing. Sam answers Mary’s phone and he and Dean head out to help Alicia and her twin brother, Max, find their mother who was hunting a powerful witch. Meanwhile, Mary starts to have some doubts about the British Men of Letters.

While working on a case involving the ghost of a demented doctor, Sam and Dean get assistance from an unexpected source – Billie. Castiel finds his way back to the Winchesters.

Dean falls victim to a couple of witches, sisters Jamie and Jennie Plum, who manage to steal a powerful book of spells from the Winchester brothers. When Sam and Dean go after the book, they get help from a powerful and surprising ally when Rowena, back from the dead, intervenes to assist them.

Sam and Charlie team up to get to the bottom of a string of random disappearances. Meanwhile, Jack believes that he has found a case and convinces Dean to partner-up with him on the hunt.

Michael has re-taken control of Dean as his army of monsters continues to move in on our heroes. Sam devises a plan to try and reach Dean and stop Michael before anyone else has to die.

Sam and Castiel follow a case to a picturesque little town in Arkansas, only to find out nothing is as idyllic as it appears to be. Dean and Jack take a road trip to visit an old friend.

Sam and Dean’s routine case turns out to be anything but.