Picking up where the finale left off, Sam and Dean must deal with the Darkness that has been unleashed. Castiel deals with the effects of Rowena’s spell and recalls his brutal battle with Crowley.

Dean helps Jenna, the deputy he met after the Darkness fell, get back home safely and then sets off to help Sam deal with a town infected by a mysterious and deadly gas. However, when Jenna falls into dangerous hands, she calls Dean for help and Sam tells him to go back to her. Unfortunately for Sam, he isn't able to handle the townspeople turned monsters as easily as he thought.

While Rowena tries to consolidate her power to protect herself from the Winchesters, Sam and Dean search for a missing baby connected to the Darkness. Meanwhile, Castiel struggles to heal and Crowley tries to find a way to use the Darkness for his own personal gain.

Seen entirely from the point of view of the Impala, Sam and Dean go on a road trip to fight monsters and demons.

Sam and Dean investigate a series of murders at a local B&B that also happens to be Lizzie Borden’s old home. When a local man, Len, tells them he saw a little girl around the B&B around the time of the murders, the brothers realize Amara may be responsible.

Castiel seeks out Metatron’s help to stop the Darkness. However, Metatron is pretty happy with his new life as a freelance videographer for the local news and isn’t inclined to help the Winchesters or Castiel. Meanwhile, Crowley is losing his hold on Amara.

Sheriff Donna calls Sam and Dean for help after a horrific murder with supernatural elements happens in her town. Sam continues to have visions and asks God for help, which frustrates Dean.

Sam is shocked when his childhood imaginary friend Sully makes an unexpected appearance. Sam can’t understand why he’d see Sully now but what’s even more surprising is that Dean can see him, too. Flashbacks reveal young Sam’s friendship with Sully and why he needed him.

Amara unleashes her power on the local townspeople as she issues a shocking challenge. Dean tries to better understand the hold Amara has on him, while Sam and Crowley come up with a plan that could have disastrous consequences.

Now that he has Sam in the cage with him, Lucifer offers Sam a way out but it comes with a steep price. Dean and Castiel look into the angel smiting that could have killed Amara.

Sam and Dean investigate a case where people are suffering violent deaths after hearing a mysterious song.

Sam and Dean drop in on Jody Mills, Claire and Alex after receiving a panicked phone call from Claire. She believes the recent murders in town are supernatural and wants the boys’ help. However, Sheriff Mills tells Sam and Dean that Claire has been getting into trouble lately as she’s been attacking normal people and accusing them of being monsters.

Sam and Dean investigate a set of murders on Valentine’s Day and discover they are dealing with an ancient curse. Once kissed by the curse, the person is marked to die.

Hoping to find a weapon powerful enough to defeat Amara, Dean convinces “Castiel,” who is still Lucifer, to send him back in time to 1944 to the fated submarine mission that sunk the Hand of God. Meanwhile, continuing his charade with Sam while they wait for Dean’s return, Lucifer plans his next move.

Sam and Dean attend a wrestling match to relive one of their fondest memories but when a wrestler turns up dead they suspect foul play.

A dangerous creature is accidentally released into an old house, attacking a mother and her child, leaving them both in a coma. Sam and Dean learn that Bobby and Rufus once tracked the same entity so the Winchesters look to the past to come up with a plan to catch the monster before any one dies.

Sam and Dean battle a pair of werewolves who have captured two victims. Just as the brothers are about to win, one of the werewolves shoots Sam. Dean gets his brother and the victims out of the house but learns a pack of werewolves are hot on their tail, hoping to kill them all.

Lucifer takes a trip home and tries to assert himself into Heaven. Crowley tells Sam and Dean he has a way to take down Amara.

In a small town in Colorado, mysterious disappearances happen every 27 years. Sam and Dean head to the town to investigate and meet two hunters who have a personal vendetta against these once-in-a-generation monsters.

Amara unleashes a dark fog on a small town, causing everyone to go mad. Dean and Sam realize this is a stronger version of the original black vein virus Amara previously unleashed. They team up with the sheriff to protect the town but their old remedy no longer works. Meanwhile, Chuck returns with an interesting proposal.

Amara shows Dean how she’s torturing Lucifer. Worried for Castiel, Dean and Sam come up with a plan to rescue him from Amara’s clutches.

Sam and Dean face their biggest challenge yet. Rowena makes her move.

God comes to a decision about Amara that has direct repercussions for Sam and Dean.

Dean is overwhelmed as he comes face to face with his mom, Mary Winchester. Meanwhile, Sam is fighting for his life after Toni, from the Woman of Letters, shot him.

Dean, Castiel and Mary have a lead on Sam and set out to rescue him. Dean is uncomfortable with putting Mary in danger but she insists on going along. Meanwhile, Crowley is tipped off that Lucifer has taken over the body of rock star Vince Vicente.

When a crying baby leads to death in a mysterious abandoned house, Mary, Sam and Dean decide to investigate. Meanwhile, Castiel’s hunt for Lucifer leads him, begrudgingly, to partner up with Crowley.

Sam and Dean investigate a case that leads them to a devout religious family that lives off the grid. The brothers realize that the parents are hiding a huge secret that could destroy them all. Meanwhile, Dean struggles to accept Mary’s latest decision.

After learning that the soul of Adolf Hitler has been trapped in a 1930’s gold pocket watch, Sam and Dean must act quickly to prevent a group of Nazi necromancers from resurrecting the Führer.

When hunters gather together to celebrate the life and tragic death of one of their own, Sam, Dean, and Mary must take action when a demon starts picking off hunters one by one.

Lucifer realizes that as rock star Vince Vincente, he can get his fans to do whatever he wants. Thrilled with this power, Lucifer arranges to play a secret VIP concert in order to kill all of them. Sam, Dean and Castiel enter the underbelly of the music industry to try to stop him.

Lucifer’s search for power and influence in a vessel lands him in the White House. The President of The United States unknowingly makes a deal with the devil, leading Sam, Dean, Castiel, Crowley and Rowena to band together to fight the Dark Lord.

After being arrested for the attempted assassination of the President of The United States, Sam and Dean must find a way out of an underground, government-run, detention facility in the middle of nowhere. Determined to find her sons, Mary and Castiel seek assistance from an unlikely source.

Lily Sunder steeps herself in black magic, honing her powers for over a century, waiting to exact revenge on a band of angels that murdered her family. Sam and Dean must work quickly to stop Castiel from becoming her next victim.

Sam enlists Rowena’s help to track down an old world, powerful family of witches after Dean gets hit by a spell that is rapidly erasing his memory.

Mary asks Sam, Dean and Castiel for help on a case she’s working but neglects to mention the British Men of Letters are involved. When Mary is double crossed, everything is revealed.

When Sam and Dean look into a murder at a museum, they learn a ghost from a merchant ship that sunk in 1723 may be at the heart of the mystery. After realizing “The Star” was the same ship that Crowley’s son Gavin McLeod should have been aboard, they enlist help from Rowena to track Gavin down. Kelly Kline, still pregnant with Lucifer’s child, takes refuge with a demon after an angel attempts to kill her.

A chance to take out a nest of vampires backfires when the alpha-vamp shows up and turns the tables on Mary and the British Men of Letters, who are doing their best to recruit Sam and Dean.

An attack by an invisible hellhound at a campsite leads Sam and Dean to investigate the mysterious circumstances. Meanwhile, two of Crowley’s own personal demons uncover what he has been hiding. Castiel gets a lead on Kelly Kline.

Sam and Dean let Mick Davies tag along on a case as they search for a werewolf. The three men run into Claire Novak, also working the hunt. However, the reunion is short lived after Claire is bitten and the brothers race to find a way to help her before she turns.

Sam and Dean get a lead on Kelly Kline’s whereabouts. Mick drops by the bunker unexpectedly and decides to join the hunt.

Sam and Dean investigate a missing person’s case in a small town. The lead witness tells the Winchesters the attacker was a man with the head of a goat. Sam and Dean aren’t sure what to believe but when the witness goes missing they realize the town is hiding a dark secret.

Sam comes up with a way to stop Lucifer’s baby but Castiel has something else in mind for Kelly. Dean is furious when he finds out someone stole the colt. Kelly makes a bold choice about the baby’s future.

Alicia Banes calls Mary for help after her mother, Tasha, goes missing. Sam answers Mary’s phone and he and Dean head out to help Alicia and her twin brother, Max, find their mother who was hunting a powerful witch. Meanwhile, Mary starts to have some doubts about the British Men of Letters.

Sam and Dean are alarmed when they learn hunters are being killed by suspicious “accidents” all over the country. They decide it is best to find Mary and make sure she’s safe. Meanwhile, Toni is back in the states and she and Mary face off.

Caught in a dangerous situation, Sam and Dean only have each other to rely on. Meanwhile, the fight between the American Hunters and the British Hunters comes to a head.

Lucifer battles Sam, Dean and Castiel for control of his unborn child.

Picking up here we left off last season, Sam, Dean and Castiel are left to defend the world after all the souls in hell have been released and are back on Earth and free to kill again.

Sam, Dean and Castiel call on Rowena to help keep the evil souls at bay and get an unexpected assist from Ketch.

Sam and Dean together with Rowena work tirelessly to keep all of hell from breaking loose. Castiel cannot forgive an arrogant betrayal.

Sam and Dean investigate the mysterious death of a girl and the disappearance of another.

Sam and Dean’s routine case turns out to be anything but.

Sam and Dean are visited by an old friend. Castiel investigates the disappearance of a local teen.

Dean goes off on his own to take on a case. Meanwhile, Castiel has an idea of how he can help Sam track down God.

Sam, Dean and Castiel’s continued search for a way to defeat Chuck leads them to unexpected places and toward unlikely allies.

Sam and Eileen are faced with the brutal truth. Meanwhile Dean and Cass work together in the hopes of getting a step ahead of Chuck.

Sam and Dean hit the road to help an old friend, but it appears that their luck may have finally run out and they are the ones who may be in need of rescue.

Sam and Dean press their luck in a winner-takes-all game of pool. Meanwhile, Castiel hunts down a would-be murderer, but not for reasons one might think.

Sam and Dean respond to a frantic call and together along with Castiel, Jack and Jody, assist in an extraordinary and heartbreaking rescue. Billie surprises everyone with a visit to the bunker.

A search for the one thing that may give the Winchesters an edge against God leads Sam and Dean to Jo’s door and to a secret that may have died with Ruby. Meanwhile, Castiel asks Jack to do the unthinkable to help the brothers in their quest.

Sam and Dean discover a wood nymph living in the bunker who is determined to protect her family, at any cost.

Castiel and Jack work a case involving members of a local church. Meanwhile, Sam and Dean go off in search of Amara.

Sam and Dean are asked to investigate the murder of a childhood friend, calling them back to a motel from their past and perplexing the brothers with a case they thought was solved a long time ago.

Dean hits the road with Jack who needs to complete a final ritual in the quest to beat Chuck. A difference of opinion leaves Sam and Castiel behind looking for answers to questions of their own.

With the plan in full motion, Sam, Dean, Castiel and Jack fight for the good of the common goal.

Everything is on the line as the battle against God continues. A familiar face returns to join the fight.

Baby, it’s the final ride for saving people and hunting things.