Syd believes that a patient she Dr. Sullivan are treating has Muchausen Syndrome which causes a mother to make a child purposely sick in order to seek immediate medical attention. Dr. Sullivan tells Syd that she was treated a year earlier and the results showed no symptoms of the disease. The doctor believes that the patient is being poisoned.

Heather asks for a off for Earth Day, Syd treats a mom to be but gives up a trip to New York but needs to help a mom to be have her baby and hope the dad will donate blood to help save the baby's life. Doug gets a new job in Ohio and asks Joanie to go with him.

Syd is unable to go to New York for a reunion and the person she hasn't seen in 10 years drops by.

Joanie meets a firefighter who she knew before, Jim falls in love with Monica and feels things are going to fast and misses Syd's call about Joanie being hurt in a fire. Robbie continues feel lucky on a game show and has no idea that he is being tricked.

Syd treats a patient who once owned an Ice Cream place where Syd worked. Robbie gets the feeling he is being tricked Syd & Joanie don't like Monica. Syd and Jim set things right.

Syd initially believes her troubled teenaged paper boy when he is seriously shot and hospitalized but he tells her that the wound is self-inflicted -- even though his older brother's behavior indicates otherwise -- and she's unaware that one of them has hidden a gun in a box of toys at the Hansens. Elsewhere, a fed-up Joanie hires an industrious clutter cleaner who systematically relieves the Hansens of their useless but memorable bric-a-brac and organizes a yard sale while Robbie meets an infomercial wizard and is inspired to create something that everyone needs.

Syd tries to compel a grieving recluse (guest star Alastair Duncan) to allow plastic surgery to correct his facial deformities when she learns that he will soon be evicted from his roost while Joanie withdraws from her family -- especially from her protective older sister -- in the wake of her recent miscarriage. Elsewhere, Robbie resorts to desperate measures in order to cozy up to the beautiful mother (guest star Maria Pitillo) of one of his adolescent hockey players (guest star Mickey Toft) while Jim struggles to coax his young granddaughter Hannah to take her medicine.

After Syd greets her old medical school pal on leave from a rural African hospital, he shows frightening symptoms of the super-deadly Ebola virus, forcing the health department to clamp a quarantine around her clinic -- as well as the Hansen household where Joanie is hosting a chaotic children's birthday party. In the meantime, while a desperate Robbie spots his family on the TV news and heads home hoping to help, Joanie discovers that his girlfriend -- who's also trapped inside the house -- was the same girl who tormented her at summer camp years before. Elsewhere, Jim busies himself treating a bulky bulldog suffering from serious anemia.