Since Jack Bauer has been pulled from his senate sub-committee hearing to assist with the deadly domestic threat and the investigation of former colleague Tony Almeida, his new undefined role is to help secure the nation. Meanwhile, President Allison Taylor presides over the escalating time-sensitive dilemmas linked to the unrest in Sangala. Chloe O’Brian and Bill Buchanan are on hand this season as well as FBI Agents Renee Walker, Larry Moss, Janis Gold and Sean Hillinger to cope with the unthinkable events

Buchanan takes Jack to "CTU", a secret hideout where he and Chloe had been working with Tony to uncover the conspiracy within the US government. Tony had been undercover with the terrorists aiding Juma to discover the moles. Jack agrees to help get Tony back in play by joining Emerson's crew himself.

Taylor is forced to meet with Matobo to inform him that she may be required to withdraw her forces from Sangala to protect American lives. Her Chief of Staff Ethan Kanin agrees with this decision, but Taylor is not yet convinced.

Henry meets with Samantha, Roger's former girlfriend, who tells him that Roger was indeed murdered and provides him with proof.

As the threat of terrorism escalates, Jack Bauer is forced to take matters into his own hands to avert the imminent crisis facing the country. Meanwhile, lives are on the line as conflicted Agent Renee Walker copes with the volatile investigation, and FBI honcho Larry Moss is forced to keep a closer eye on his team as the nation's security is in jeopardy. At the White House, international stakes are raised and the First Gentleman proceeds with his personal mission.

As Dubaku presses President Taylor to comply with his devilish demands, she contemplates if the administration should negotiate to avert a disastrous terror attack. Meanwhile, away from the White House and the threatening international crisis, the determined First Gentleman struggles with his ongoing domestic mission, and perilous FBI Agent Walker diverts the attention of her tense colleagues. With national security on the line, Jack Bauer has a formidable plan in hopes of shielding the country in the “Day 7: 1:00-2:00 PM” episode.

As U.S. troops remain in position outside of Sangala, Dubaku seeks another high-value target using the CIP module. While the entire NSA scrambles to locate the breach, the situation rapidly escalates. Paranoid FBI Agent Janis Gold commands from her post, while Jack, Tony, Renee, Chloe and Buchanan follow leads.

As the country reels from the recent terror attacks and faces the mounting global ramifications, the administration refuses to acquiesce and presses on with their disapproval of the Juma regime. As Jack Bauer and team head to the White House for a pivotal meeting with President Taylor, Dubaku raises the stakes when he threatens the First Family