Co-eds are being murdered on a small university campus, all drained of their blood with two small marks on their necks. The late Professor Pendergast, who had been investigating the idea that vampirism is caused by a blood disease, has been sighted at two of the attacks.

Terror ensues when Ellen Alexander wakes up alone in a hotel room, with no sign of her husband, Harry. Inquiries at the front desk yield the answer that he has checked out without her, and eventually lead her to Brett, who helps her find the answers she is seeking.