A 100% fatal and 100% contagious plague is killing the Markabs. Dr. Franklin tries to find a cure, but is being opposed by the Markabs themselves, who believe the plague only affects the immoral.

Lyta Alexander returns to Babylon 5 with a message from the telepath resistance: one of the command staff is a mole for PSI Corps.

Draal reveals himself to Sheridan, while Refa and Londo set a plan in motion that will lead to the final defeat of the Narns.

Kosh summons an inquisitor to test Delenn's motives, and G'Kar tries to maintain his position as leader of Babylon 5's Narn population while organizing an underground resistance.

Two officials from the Ministry of Peace come to Babylon 5; one to deal with the Centauri's continued expansion, and the other to check on the local Nightwatch. Meanwhile, a Narn heavy cruiser seeks sanctuary while they make repairs, and Keffer continues his search for proof that Shadow ships exist.