When Trip suffers a catastrophic injury, his only hope for survival is a transplant from a "mimetic symbiont" which Phlox grows from one of his exotic creatures.

Religious zealots hijack Enterprise to use it as a weapon against the enemies of their faith.

Archer sets out on a suicide mission to destroy the Xindi superweapon as Enterprise faces a brutal attack.

Archer and Hoshi stand before the Xindi Council as T'Pol and Reed lead a team into the heart of a Sphere.

Archer and the NX-01 find themselves in Earth's past, with events of World War II altered by the Temporal Cold War.

With Silik's help, Archer hones in on the temporal operative who altered Earth's past and threatens to destroy all of time.

Archer tries to unify the Andorians, Tellarites and Vulcans in a plan to capture a marauder ship threatening to destabilize the region.

Archer visits Shran's icy homeworld to find an Andorian subspecies called the Aenar, to determine their connection to the marauder destroying ships in the region.

While Enterprise visits Earth for the launch of Columbia, Phlox is kidnapped and forced to help the Klingons deal with a grave threat toward their species.

As a gift for negotiating with the Orion Syndicate, Captain Archer receives three Orion Slave Girls.

A xenophobic faction of humanity threatens to undermine talks to form a new coalition of planets.