With the invaluable information that was shared by Agent Jenna Kaye, Five-0 is closer than ever to capturing Wo Fat. Their mission takes an abrupt turn, however, when Danny is exposed to a lethal neurological agent that presents an even greater threat: bio-terrorism on the island.

While McGarrett sits in prison awaiting trial for the murder of the governor, Danny brings him a surprise visitor to help clear him. Meanwhile, Kono is suspended from the force, pending an internal investigation.

The FIVE-0’s investigation into the murder of the state’s women’s volleyball coach leads them to find out more bad news about Kono, and Chin Ho reconnects with his former fiancée, Malia.

FIVE-0's investigation into the suspicious plane crash and death of a customs agent takes an unexpected turn when it is revealed that the victim was dead before takeoff. Meanwhile, Danny finds himself the proud caretaker of an orphaned dog.

When the Five-0 team discover that the murder of a High School girl was a professional hit, they must find out why she was targeted before they can find her killer.

Five-0 investigates the murder of a man dressed as a Hawaiian NaKoa warrior found in the jungle near the site of a historical war reenactment

Five-0 is in hot pursuit of a shooter who guns down one of their own, while another team member is forced to choose which of their kidnapped loved ones will live.

Steve and Danny take some time off to enjoy a little fishing only to find themselves stranded and facing pirates.