The Chief tries to help a boy who has aged rapidly. Meanwhile, Blake tries to help people via the healing power of laughter.

Blake challenges Nate to a competition where the two doctors must perform surgery using only the healing power of laughter.

Dr. Maestro asks Dr. Flame to give him a lethal injection so that he can find Dr. Spratt in the spirit world. A creepy EMT wants to show The Chief his "sexy costume.