As Komachiyo flees with Luffy, Zoro, and the ill Tama, Hawkins pursues them with the straw entity. Zoro defends against the straw entity's attacks and eventually defeats it. After the group escapes from Hawkins, Tsuru, who had been hiding inside Komachiyo's tail, reveals herself and invites the group to her teahouse in Okobore Town, where she can help Tama.

Luffy faces against Urashima in a sumo match. Holdem tries to pull off Tama's cheek until Luffy sends Urashima crashing into Holdem's residence.

The drunken Kaido flies above Okobore Town in his dragon form and threatens Shutenmaru and all the people in the town. Luffy, Law, Kin'emon, and Kiku start running towards the town to rescue them. However, Kaido heads towards the ruins of Oden Castle and destroys it with a single attack.

Zoro goes to a gambling house with Tonoyasu. After a brawl, they go to Ebisu Town. Meanwhile, the Ninja-Pirate-Mink-Samurai Alliance works to steal weapons and food. Franky learns that Minatomo no longer has the blueprints of Kaido's mansion. He goes all over the Flower Capital searching for them but hits a dead end. At the shogun's castle, CP-0 attempts to negotiate with Orochi.

At the Excavation Labor Camp in Udon, Luffy tries to save Old Man Hyo and stands up to Vice Warden Daifuku and Warden Babanuki with his physical strength weakened by the Sea Prism Stone cuffs. Then when a Lead Performer of the Animal Kingdom Pirates, Queen the Plague, comes to the camp, Luffy makes an escape!

Big Mom subdues Queen when the latter tries to fight her. During that scuffle, Kid and Killer are saved from drowning. Big Mom does not find any oshiruko, and when Luffy blurts out that he ate it, she attacks him out of rage. Luffy and Hyogoro are forced out of the ring, but Luffy manages to remove the collars before they are killed. Afterwards, Hyogoro decides to test Luffy by having him defend against Big Mom's attack.

Enraged by Orochi’s tyrannical acts, Oden raids his castle in the Flower Capital and points his sword at Orochi. However, hours later, people who were waiting for Oden to come out after defeating Orochi see the unexpected. Meanwhile, the King of the Pirates Roger’s execution and last words are printed in newspapers and spread across the world.

Luffy and the rest of the Straw Hat crew are excited to see Jimbei again and welcome him as a new member. Meanwhile, Law and the Akazaya members strategize on how to enter Onigashima and attack Kaido. As the Straw Hats approach the giant torii gate in front of Onigashima, they are attacked out of the blue.

Evading Ulti and Page One, strong members of the Tobi Roppo, Luffy tries to find out what Kaido’s son Yamato’s motive is. However, the two get in a fight. Taking Luffy’s punishing attacks, Yamato remembers someone he fought against in the past.

Franky faces Big Mom with the help of Robin and Jimbei, but the Numbers come interrupting their battle. One of them holds Brachio Tank with Usopp and Chopper inside in his hand. Meanwhile, Yamato, the self-proclaimed Oden, finally meets his son Momonosuke.

Carrot and Wanda step in to help Marco, who is cornered by Big Mom and Perospero. In the meantime, Yamato fights a fierce battle against the Animal Kingdom Pirates Armored Division led by Sasaki, while protecting Shinobu and Momonosuke.

Chopper works hard to make the cure for Ice Oni, even though he is turning into one himself. Meanwhile, the infected Boss Hyogoro the Flower regains his youth and fights fiercely to protect Chopper and the others.

Luffy amps up the reluctant Momonosuke, who is afraid of heights, in his giant pink dragon form, to fly and take him to Onigashima in the sky. Meanwhile, Yamato, in a hard battle against Kaido, vows to survive until Luffy returns.

Zoro is facing a hard fight against King who seems invincible. Even one of Zoro’s deadliest attacks doesn’t leave a scratch on him. On top of that, one of Zoro’s swords goes out of control and gets in his way.

The battle between Luffy and Kaido comes to an unexpected end. Kaido comes down and tells everyone that Luffy has been defeated and the Land of Wano is finished. Momonosuke and Yamato argue over whether they should still continue fighting.

Luffy and Chopper fall into the rough cold sea along with the mysterious girl. Jimbei tries to help them but another attack comes from the unknown creature. Meanwhile, the Sunny is hit by torpedoes and the rest of the Straw Hats are thrown into the sea, too.

Vegapunk asks the Straw Hats to take him on board their ship which makes Franky and Usopp happy but annoys Nami. Lucci orders his troops to block off all Vegapunk’s escape routes and looks to invade the heavily-secured Labophase.