In rural Arkansas, Frank investigates the owner of a daycare center accused of child abuse, only to be accused himself.

Millennium Group offender profiler Frank Black investigates the abduction of a bus full of schoolchildren, requiring the help of fellow Group members Peter Watts and Lara Means as he tracks a man preparing for a third world war.

As Christmas approaches... Frank experiences visions from his childhood when Jordan claims to have been visited by the spirit of her dead grandmother.

Serial murders in the guise of assisted suicides stymie Frank, whose primary suspect is a charismatic hospice nurse. Frank and Lara investigate to determine if it is murder.

The discovery of the remains of the Crucifixion Cross threatens to divide the Millennium Group.

As the schism between the two warring Millennium Group factions deepens, Frank discovers the existence of yet another player in the power struggle.

A mysterious Asian woman is linked to several strange deaths aboard a ship.

Catherine and Lara investigate when five girls claim they saw a vision of the Virgin Mary.

In Wisconsin, in 1986, a farmer discovers thousands of dead birds inside his chicken coup warehouse, pools of blood encircling each cage. The farmer races for a phone, but collapses on his hands and knees, black papules having grown over his lymph nodes.

In this continuation of the previous episode... Jordan, Frank and Catherine bury the dead parakeet, prompting more questions from Jordan regarding God and the hereafter. Later, a Millennium team clad in bioharzard suits sweeps into the Davis home, where earlier an entire family was wiped out by the mysterious virus. Outside the house, in the backyard, are a dozen dead birds of various species.