Eric helps out a woman who is being abused by her husband. But when the good reverend is seen escorting the woman to a motel one afternoon, it's the talk of the town. Meanwhile, Matt warns Mary about an older guy she's seeing.

Lucy is spending the weekend at camp 'All By Myself'. It turns out everyone at the camp has to spend the weekend all by themselves without talking to anyone. Ruthie is angry with classmate Bobby Tripp because he keeps making fun of her since he accidently saw her underwear. Now, Ruthie decides to make him realize what he did was wrong by starting a war: Camdens vs. Tripps. The church's women group throws a baby shower for Annie. Eric and Matt have lunch with Morgan and John Hamilton. The manager of the restaurant doesn't serve Morgan and John their meal because he doesn't serve black people.

Eric develops a child-like fascination with life when he takes a much-needed vacation after his heart attack episode, while Annie runs into interference with each of the kids. Meanwhile, Simon assumes the role of the 'man of the house', but feels Matt is undermining his authority when he keeps on making fun of him. Also, Matt grows uncomfortable with the blossoming friendship between his girlfriend Shana and his roommate John Hamilton while he's busy with other issues. Also, Lucy finds a direction in her life with her interest in Habitat for Humanity after taking her fathers advice.

Mary's future may be resolved, but the rumor mill surrounding her situation runs rampant. While ugly rumors spread about Mary's sudden departure, Simon is persuaded to use his sister's bad reputation to boost his 'cool' quotient at school and gets into some trouble of his own with identical twin bad girls, Carol and Sue Murphy (Mary Kate and Ashley Olsen, Full House). Congregational gossip irks Eric. Lucy wrestles with high school hearsay. Ruthie spreads phony tales to draw attention away from Mary, and Matt's infatuated with a beautiful stranger. Also, Annie goes out with an old boyfriend.

When new mom Lucy welcomes guests over to see the baby, Annie immediately becomes concerned, believing that Lucy doesn't fully understand the health risks of exposing a newborn to strangers. Lucy's determination to show everyone that she has parenting under control leaves Kevin to question his role as a father, especially when they're alone. Also, struggling new parents Kevin and Lucy move back into the Camden home, while Martin moves into the garage apartment.

Eric is worried that he and Annie are doing too much in helping Kevin and Lucy adjusting to parenthood as they're taking on more than they should as grandparents. Meanwhile, Martin's classmate Zoe (guest-star Katie Cassidy) intentionally falls asleep on the couch of his apartment so that she can tell everyone at school that they slept together. When Ruthie finds out about Martin's overnight guest she sees it as the perfect opportunity to blackmail him into getting her a date with her crush, Vincent (guest-star Thomas Dekker).

Eric, Annie and Ruthie are on their way home from Scotland, but they are held for questioning at the airport after Ruthie makes an unusual comment. Elsewhere, as a favor to Martin, Mac seeks information about Sandy's feelings for Simon. Lucy does her best to stay strong for the whole family as the truth about her father's health condition comes out.