Shinichi Chiaki was almost giving up his dream of becoming a conductor, until he met Megumi Noda, also known as "Nodame". The pieces performed in the episode are Introduction and Rondo Capriccioso by Camille Saint-Saëns (brief), Piano Concerto No. 5 in E-flat major "Emperor" by Ludwig van Beethoven (brief), Piano Sonata No. 8, Op. 13 "Adagio Cantabile" by Ludwig van Beethoven (brief) and 2-Piano Sonata in D Major, K.448/375a by Wolfgang Amadeus Mozart.

Ryutaro Mine is a violinist who needed a piano player for his violin jury. But when he chooses Nodame as his partner, little did he know his troubles were just beginning. The piece performed in the episode is Sonata No. 5 "Spring" for Violin and Piano, Op. 24 by Ludwig van Beethoven.

A foreigner visits Chiaki's school and becomes friends with Nodame. Chiaki refuses to let him into his house because of his perverted behavior. It turns out the foreigner is Maestro Franz von Stresemann and is attending the school as head of the conducting department. Chiaki, interested in changing his major to conducting, gets rejected by the new professor who is apparently at odds with Chiaki's former "teacher", Vieira. The piece performed in the episode is Fantaisie Impromptu, Op. 66 by Frédéric Chopin (brief).

With Stresemann knocked out cold, Nodame "convinces" Chiaki to be substitute conductor for the special orchestra. Chiaki agrees and finds out that the group he's conducting is out of synch. As the rehearsal falls apart, Stresemann takes over and demonstrates everything that Chiaki failed to do. Stresemann finally accepts Chiaki as his student but tells him to remain a piano major. The piece performed in the episode is Symphony No. 7, Op. 92 by Ludwig van Beethoven.

Chiaki is still having trouble getting the orchestra into shape, and everyone's confidence shatters under his harsh criticisms. With help from Nodame, Chiaki finally realizes Stresemann's reasoning behind the S Orchestra just in time for the concert subscription series, and the S Orchestra manages to impress their audience with an unorthodox display. The piece performed in the episode is Symphony No. 3 Op. 55 "Eroica" by Ludwig van Beethoven.

Chiaki is asked to leave the S orchestra to play the piano solo of Piano Concerto No. 2 by Sergei Rachmaninoff as requested by Stresseman for the A orchestra. It is revealed that Stresseman was asked by his ex-lover, a member of the academy's board of directors to instruct Chiaki in conducting. The piece performed by Nodame towards the end of the episode is Etude N° 4 in C Sharp Minor by Frédéric Chopin. The short piece that was played by Stresseman's ex is an excerpt from Nocturne Op 55 No. 1 in F minor, also by Frédéric Chopin.

The school festival is here and the S Orchestra is to perform without the aid of Chiaki, who is busy practicing with the A Orchestra with their performance. Chiaki discovers what was missing from his playing courtesy of the S Orchestra, but Stresemann tells him to disregard it for their upcoming performance after insisting on it throughout all his practices. The pieces performed in this episode are Piano Concerto No. 2 by Sergei Rachmaninoff (brief) and Rhapsody in Blue by George Gershwin (pianica version).

It is finally Stresemann, Chiaki, and the A Orchestra's turn to perform for the school's fall festival. They manage to captivate the audience with their Rachmaninoff performance. Chiaki and Stresemann go their separate ways as Stresemann returned to Europe the next day. Nodame becomes desperate to perform in an orchestra like Chiaki and is left with a message and present from Stresemann. Saiko, still thinking about Chiaki, comes by for a visit. Nodame also comes by after practicing Rachmaninoff for days without bathing and hardly any food. The piece performed in this episode is Piano Concerto No. 2 by Sergei Rachmaninoff.

It's graduation time at the Momogaoka College of Music and its graduating students (including Chiaki and Masumi) put on a performance of various classical pieces for their graduation recital. Kiyora, the former concert mistress of the Nina Lutz Seminar Youth Orchestra, proposes to Chiaki her idea of assembling an orchestra. She invites Chiaki in as their conductor. Needless to say, she also requests that Chiaki and his "superstar" status to invite some of the elite musicians (cellist, violinist, and oboist) into the orchestra. The S Orchestra has their final get together as they disband and move on. The pieces performed in the episode are Concerto for Flute and Percussion by André Jolivet and Mephisto Waltz No. 1 (Der Tanz in der Dorfschenke) by Franz Liszt.

Under rather bizarre circumstances, Nodame makes a visit to the home in which Chiaki grew up, meets his family, and even makes dinner for them (onigiri and nabe). Since the passing of Chiaki's grandfather, tensions seem to have risen within the family, nearly to a breaking point. The pair end up staying over night, and when a nightmare wakes Chiaki, he retreats to his grandfather's audio room. Upon waking to the sound of the opera, Nodame finds Chiaki in the study, listening to records. Eager to play, she convinces him to accompany her on the violin while she plays the piano. There are no pieces performed in this episode; however, Chiaki listens to Matthäuspassion by Johann Sebastian Bach in his Grandfather's audio room.

The R-S Orchestra starts rehearsing for their first concert, while Nodame and her new teacher finally come to an agreement. The piece played is Mozart's Oboe Concerto in C major K 314.

Nodame finishes her last "Moja Moja" song and now must do her part in her deal with Etou sensei. Meanwhile, some members of the R-S Orchestra take a break on rehearsals to dedicate to their solo competitions. The piece performed in this episode is Symphonie Espagnole, op. 21 - 1. Allegro non troppo by Édouard Lalo.

After the concert, Nodame uses hypnotism to cure Chiaki's fear of flying. The pieces performed in this episode are Symphony no.1 in c minor by Johannes Brahms, Piano Sonata D845 by Franz Schubert, and Transcendental Etude No. 5 "Feux Follets" by Franz Liszt.

Nodame advances through the preliminaries of the Maradona piano competition, while the R-S Orcherstra's fame increases, drawing more and more attention. The pieces performed in this episode are Piano Sonata D845 by Schubert, Prelude and fugue no.16 (only the fugue) WTK book 2 by Bach, Etude Op. 10, No. 4 by Chopin, Transcendental Etude No. 5 "Feux Follets" by Liszt and L'Isle Joyeuse by Debussy.

Nodame is in deep trouble as her train of thought is robbed at an unfortunate moment. She leaves the competition hall disappointed as well as Chiaki who had hoped she would goto Europe with him. The New Year's concert is around the corner and Chiaki has yet to inform the Rising-Star Orchestra of his pending departure from Japan as well as his replacement conductor, Matsuda. Sakuma also shares his reasons as to why he had helped Chiaki throughout his past 2 years starting from his Rachmaninoff performance. The pieces performed in this episode are Petrushka by Igor Fyodorovich Stravinsky, Prélude à l'après-midi d'un faune by Claude Debussy, Carmen Fantasy by Pablo de Sarasate, and Till Eulenspiegels lustige Streiche Op.28 by Richard Strauss.

A 15-minute special that takes details a detour Chiaki, Nodame, Mine, and Masumi take to the mountains on their way to the music festival.

Chiaki takes part in his first competition as a conductor. But he ends up having to face strong contestants like Jean Donnadieu, one of Sebastiano Vieira's apprentices.

Nodame and Chiaki meet Stresseman in Paris. Chiaki starts to travel the world attending concerts with Stresseman after being forced to sign a contract with his manager, while Nodame has her first class with an acquaintance of hers at the conservatoire.

Chiaki rehearses for his debut concert in Paris, and finds that Nodame is troubled as she is not doing fine at the conservatoire. While he tries to cheer her up, their relationship ends up moving a little forward.

Kuroki was having trouble to adapt himself to life at Paris until he meets Nodame at the conservatoire. Meanwhile, Chiaki is feeling insecure as Nodame does not answer his phone calls and wonders if both will really be able to spend Christmas together.

Chiaki is appointed as the official conductor of a famous orchestra which is facing serious dificulties, and Son Rui, a famous pianist who is an old friend of his, gives a break on her performances to study at the conservatoire. However, Rui's closeness to Chiaki is more than enough to ignite Nodame's jealousy.

The Marlet Orchestra is short on staff, and Chiaki asks Nodame to take a part on it. However, Nodame's dreams of having her first performance along Chiaki are crushed when Rui is forced to assume her place due to a misunderstanding.

Disappointed with his first performance, Chiaki starts scouting for new musicians and invites Kuroki for an audition. Meanwhile, Rui is forced by her mother, Mrs. Son, to leave Paris with her, after she heard from Madame Bellou (possibly Rui's landlady) that she's been slacking off and spending time at Chaiki's. While Nodame rehearses for the exams at the conservatoire along with Kuroki and Paul duBois.

Nodame travels to Saint-Malo with Chiaki, Tanya and Kuroki for her very first recital. However, her companions are worried about her insecurity, as she usually has trouble in playing pieces by Mozart.

Auditions are held for the Marlet Orchestra, with Paul and Kuroki being among the new members. After intense rehearsal, the Orchestra has another concert, and the time comes for Chiaki to show the results of his ad his musicians' efforts so far.

Chiaki decides to move to another apartment much to Nodame's despair and Rui tries her best to convince Auclair to have lessons with her, but he seems to be more much more interested in teaching Nodame instead. After hearing Nodame's smooth playing, she also starts to doubt herself. Pieces featured: Sonata K157 in C Major by Scarlatti, Nocturne Op. 9 No. 2 in Eb Major by Chopin

Thanks to Chiaki's encouragement, Rui decides to keep playing and a special concert featuring both is arranged. Stresseman is seriously depressed over the death of a friend of his and Chiaki, on the way to attend one of Nodame's recitals, have a surprising reunion with Sebastiano Vieira and he decides to accompany him instead. Pieces featured: Italian Concerto, BWV 971 by Bach, Op. 19 No. 1 "Sweet Remembrance" from Songs without Words by Felix Mendelssohn, Polonaise Fantasie by Frédéric Chopin, Légende No. 1: St François d'Assise by Franz Liszt

Tanya starts to feel jealousy when Kuroki is asked to take care of a young japanese girl who is trying to enter the conservatoire. While trying to get closer to him, she starts to wonder about her own future as she is near her graduation.

Tanya and Yu Long have poor performances at the competitions they took part, and thus they will be forced to return to their respective countries after graduation. While trying to cheer Tanya up, Kuroki ends up making a surprising proposal to her. Meanwhile, Nodame hears a piece of music that draws her attention. She hopes to play it along Chiaki someday, unaware that it's the same piece that will be featured at Chiaki and Rui's concert.

Nodame finds that Chiaki has hidden from her the connection between the piece and his concert with Rui and she can't hide from him her dissatisfaction for not telling her sooner. After looking at how much difficult pieces Nodame is studying with her teacher, Chiaki cancels an important trip to Italy just to lend a hand to her.

Chiaki helps Rui for their concerto. When Nodame found out, she feels betrayed, and uses that feeling to help her master a piece. Pieces featured: Paris Symphony by Mozart, Third Movement of Piano Sonata No. 31 by Beethoven

Nodame has been absent from school and Chiaki starts looking desperately for her, just to find that she was rehearsing for a concerto with Stresseman in London. Pieces featured: Piano Concerto No. 1 in E minor, Op. 11 by Chopin

DVD special episode taking place before Episode 1 of Finale that focuses on Miki Kiyora making it to the final round of a competition in Paris.