Carter fumbles his way through his first look at surgery. Dr. Lewis' nemesis, Dr. Kayson, makes her New Year's Day decidedly unpleasant. Chloe announces she's moving to Texas with her boyfriend.

Carol worries about a Russian girl with AIDS who's brought in and then abandoned by her foster mother. Kayson asks Susan to be his Valentine. Deb accidentally consumes LSD-laced chocolates.

Dr. Hicks berates Benton when he tries to switch shifts to attend his mother's birthday party. A teenage girl, a frequent patient of the ER, is brought in for a drug overdose. Carol decides she wants to adopt Tatiana while Tag isn't so sure. Dr. Ross slugs an abusive father in the lobby. Jen accepts a job offer in Milwaukee despite Mark's offer from Morganstern. Deb and Carter await the arrival of sub-internship applications.

Susan is forced into the role of parent when Chloe gives birth and both Chloe and her mother, Cookie, shirk responsibility. Doug is surprised and a bit frightened when Diane suggests they move in together. Unfortunately, Linda Farrell happens to be around to take advantage of his nervousness. Carter is offered the ER sub-I but turns it down in anticipation of receiving a surgical position. Peter receives unpleasant news; his mother has died.

Kerry Weaver manages to offend just about everyone in her first day as chief resident. Carol goes on a ride-along with paramedics Shep and Raul, sharing a ferris wheel ride with Shep. Peter and Jeanie's secret relationship comes to a head. Susan is stuck caring for Little Susie while Chloe attends school. Dr. Ross has his hands full with a young pyromaniac. Carter shows interest in med student Harper Tracy.

Speculation runs through the ER, on a very hectic day, about Randi's possible criminal history. Mark faces an ethical dilemma when he has to decide whether to report yet another of Doug Ross's indiscretions--Doug slept with med student Harper Tracy. Carter becomes upset when Harper confesses this to him. Carol meets with a mobile notary to finish the paperwork to purchase a house. Bernstein informs Doug that he need to look for other employment. Benton is visibly upset when Jeanie begins work in the ER as a physician's assistant.

Benton decides to blow the whistle on Vucelich's unethical study methods, causing Vucelich to drop him from the study. Susan treats a street couple, one of whom has passed HIV to the other. Doug receives a visit from his estranged father. Carter spreads rumors about an affair between Mark and Susan. Mark buys a motorcycle. Prostitute Loretta has cervical cancer.

Susan visits a psychiatrist to cope with the loss of Little Susie. Jeanie's estranged husband Al checks in the ER complaining of flu-like symptoms, which turn out to be caused by HIV. Shep expects Carol to back his version of events during an official investigation of his behavior. Loretta takes a turn for the worse. Doug discovers that his father has disappeared with a LOT of Karen's money.

While the whole staff is worried the ER might close, Jeanie has her own problems in dealing with being HIV-positive.

Nurse Carol Hathaway is held hostage during a convenience store robbery, then befriends one of the gunmen.

It's Carol's birthday, Mark is returning to work after being assaulted and Carla goes into premature labor.

Carter is exited about getting his own med student and Mark and Carol interview candidates for the desk clerk position.

Ross and Hathaway's jobs are in jeopardy after their unauthorized treatment of a drug-addicted 7-month-old boy is discovered. Corday loses her sponsorship. Carter suspects Del Amico's boyfriend when drugs are stolen.

Third-year med student Lucy Knight reports to the ER for the first day of her rotation. Greene takes a teacherly interest in her, helping her get acquainted, but she gets off to a bad start with the irritable Carter when she speaks insensitively, and without Carter present, with a patient's wife about her husband's very serious condition. The rest of the day finds her comforting a woman who has suffered a miscarriage, getting locked out on the roof, having Carol bail her out on a simple procedure, and trying to figure out Kerry Weaver's "Tour on Tape."

Carter plays tour guide for Ruth Johnson, who was born in the hospital 100 years ago to the day, and her large family. Carol treats a boy who was hit by a car and tells a story of being chased, his friend being shot in the process. Peter observes Kotlowitz install a cochlear implant and decides to wait before scheduling an operation for Reese. Mark dines with Dr. Lee, new ER chief. Dr. Corday proposes radical changes in scheduling at an M&M conference, and later decides to break off her relationship with Benton.

Ricky Abbott returns to the ER. Doug forges papers to allow Joi to treat Ricky at home. Corday decides to back out of the Romano sexual harassment investigation after he threatens to expose her relationship with Benton. Romano is later named Acting Chief of the ER. Dr. Greene treats a Nigerian janitor for back pain and impotency. Carol and the nurses watch a bunch of dogs when their owner is hospitalized. Carter diagnoses a med student with Hodgkin's disease. Kerry initiates a search for her biological parents.

Carol's pregnancy becomes public knowledge as she learns that she's having twins. Lucy has problems trying to go off Ritalin. Peter learns Carla plans to move to Germany. Kerry finds an abandoned youngster and brings him to the ER. Mark and Elizabeth discuss their relationship. Jeanie and Reggie draw closer again.

When Anspaugh decides to retire as chief of staff and return to surgery, he appoints Romano as his replacement. Greene expresses reservations about the decision, but Weaver does not support Greene. Romano makes Weaver the new chief of emergency medicine.

Dr. Greene and Corday bond with their parents, Lucy cares for a patient with a psychotic break, and Valentine's Day celebrations in the ER end tragically for one of the students.

Carter seeks psychiatric help because he can't sleep. He then visits the wife of his attacker. Weaver returns to work after her suspension. Hathaway and Kovac share a kiss.

A rape victim, barely able to speak, does all she can to help police find her attacker.

Dr. Weaver meets her birth mother, but their relationship changes when Kerrie reveals she is gay. Dr. Carter causes a commotion when he confronts a couple hoping to scam some painkillers.

Jules 'Ruby' Rubadoux is back in the ER. He's still angry with Carter about the death of his wife.

Pratt departs for Africa with attitude to spare but makes his first contact with harsh reality before the plane lands. Abby senses something is not what is seems when she treats a 12-year-old and her grandmother, then differs with Luka over the best course of action. A prisoner is brought to the ER with what everyone thinks is a fake case of appendicitis. Morris is dressed, and ready, to impress, but Albright’s not. It’s time for Kerry to return to work and Clemente doesn’t know when it’s time to leave.