The hospital suffers through a series of power outages. Carol's decision to send Doug a fax about her pregnancy is thwarted by the power outages. The staff is on alert after a raped and beaten patient is found in a hallway. Romano begs Corday to stay in trauma. Carter and Roxanne break up. Carter and Lucy treat a pheromone saleswoman.

Lucy's patient finally gets a heart transplant but does not survive. The transplanted heart will now go to another recipient. Greene interferes in a gay domestic situation. Corday tricked her patient who murdered several women and now he's being transferred to a county jail.

Even though he suffers from intense pain due to his stabbing injuries, Carter returns to work and prescribes a controversial procedure for a suicidal patient. Greene tries to convince his father to undergo cancer treatment.

As the result of a school shooting, Kovac and Benton care for the gunman and his victims. Abby discovers that Carter has been illegally injecting pain relievers. Greene and Weaver confront Carter about his problem, and Weaver orders him to enter a drug rehabilitation center or leave the hospital permanently.