Red and the Task Force place Dembe undercover to infiltrate an international human smuggling organization, but when communication is lost, they must intervene. Meanwhile, Tom's investigation into the suitcase lands him in grave danger.

Tom goes missing and Liz desperately retraces his steps to find him; Red's hunt for the suitcase of bones leads to lives being changed forever.

When Red directs the Task Force to find a Blacklister who uses his position of power to sell sensitive information, Ressler finds himself at risk of exposure. Meanwhile, Liz plans her next move.

When Red goes on the hunt for a legendary treasure, he draws the attention of Abraham Stern, a cunning manipulator who has devoted his life - and the lives of many innocents - to recovering the fortune that is his birthright. Meanwhile, Liz's quest sends her down a dark path, leading her to study the methods of one of the Blacklist's most dangerous criminals.