Detective John Kennex and Dorian respond to a suspicious death at a hospital where - before having a fatal cardiac arrest - a man claimed someone was trying to kill him, and inexplicably knew his exact time of death. As the investigation unfolds, a black market for vital organs is uncovered in which bio-mechanical hearts can be resold and remotely "shut off." As the team fights to find the pulse of this 2048 tech-centric crime, Dorian reconnects with a decommissioned DRN

Det. Kennex and Dorian investigate Simon, a psychopathic killer who is strapping bombs to his victims' neck and broadcasting their final moments over the internet. When Simon targets Kennex, the team is in a nail-biting race against time to save his life. Meanwhile, a power deficiency affects Dorian's energy level, causing him to have unexpected outbursts

A series of murders are committed by someone copying a serial killer who was put in jail by Kennex's father.