The Turtles and their enemy crash-land on an ice moon and they must put aside their differences in order to survive.

When Mona Lisa suddenly arrives on Earth, Raphael must get her and Bishop to work together to defeat an alien threat and save the Earth

The Newtralizer returns to New York City, more powerful than ever before, and joins forces with a dangerous and unexpected ally. With the help of Raphael's Salamandrian girlfriend, Mona Lisa, the Turtles fight back to defend their city.