The Doctor has regenerated into a brand new man, but danger strikes before he can even recover. With the TARDIS wrecked, and the sonic screwdriver destroyed, the new Doctor has just 20 minutes to save the whole world - and only Amy Pond to help him.

The Doctor receives a distress signal from an old friend. Could there really be another living Time Lord out there? Hopes raised, he follows the signal to a junkyard planet sitting upon a mysterious asteroid in a Bubble universe, populated by a very strange family, as the time-travelling drama continues. The Doctor, Amy and Rory are given the warmest of welcomes by Auntie, Uncle and Nephew. But the beautiful and insane Idris greets them in a more unusual fashion – what is she trying to tell the Doctor? As the Doctor investigates, he unwittingly puts his friends in the gravest danger.

A little boy named George sends a distress signal to the Doctor when he discovers that monsters live in his bedroom cupboard.

The TARDIS brings its crew to a quarantine facility for victims of an alien plague. When Amy is trapped, Rory must rescue her from the facility's doctors but learns something surprising about his wife.

The trio arrive at a hotel where the layout of the rooms keeps changing. It also contains rooms that hold the greatest fears of each visitor.