Juliana Crain makes a new acquaintance in the Neutral Zone - an Irish fixer named Wyatt - and soon finds herself on the run and seeking Tagomi's aid. The Japanese test an atomic bomb. Joe Blake is sent on a diplomatic mission to San Francisco. Kido hires a new sergeant. Nicole Dormer arrives in New York to head a new propaganda campaign. The Smiths struggle with the aftermath of Thomas' death.

With Wyatt's aid, Juliana flees San Francisco with the stolen Nazi secrets. Childan can finally return home; Ed decides to stay in the Neutral Zone. Tagomi makes revelations to Kido that change Kido's perspective. John Smith's career takes a turn.

Juliana embarks on a mission to stop the Nazis - a mission that reunites her with old friends. Thelma and Nicole grow closer, despite the risks. Smith learns more about the Nazis' efforts into alt-world travel. Kido demands Tagomi come clean about the films and his ability to travel. Kido coaxes crucial intelligence from Childan.

Juliana and Wyatt's mission takes them farther east and dangerously close to the center of a top-secret Nazi project. Trying to improve relations between their sides, Tagomi reaches out to Smith. Smith makes a crucial discovery. Kido finds closure.

Juliana's attempt to stop the Nazis lands her in a precarious position. Himmler and John Smith lead a lavish celebration of Year Zero. Amid a series of successes, Smith faces a setback. Kido returns to San Francisco with a prize, performs an act of kindness for a friend. Tagomi makes a difficult decision. Ed returns to San Francisco and reconnects with Childan.

John and Helen host Himmler and his wife for dinner, along with a new and dangerous threat from Berlin, Obergruppenführer Goertzmann. Juliana returns to the High Castle world, arriving in the ruins of what is now known as “The District of Contamination.” Kido is forced to turn against the Crown Princess by his general. A captive Hawthorne Abendsen shares some new tales from the High Castle.

Juliana’s instincts about Helen are put to the ultimate test. As San Francisco evacuates, Kido goes in search of his son, only to find himself a captive. A letter arrives, forever changing Childan and Yukiko’s lives. The BCR receives an unexpected offer of help from the Yakuza. Abendsen condemns Smith with his final prediction.