Cottonmouth strikes back at Luke by taking his vengeance out on the people of Harlem, while detectives Knight and Scarfe face an unexpected threat.

After Cottonmouth and Scarfe's bloody clash, Luke realizes that saving the community may turn former allies into enemies, and enemies into allies.

Mariah's political career comes under fire, and Cottonmouth picks up information that could put Luke on the run.

Mariah campaigns to turn the city and the police against Luke, and not even Misty or Claire may be able to save him.