Dr. Choi treats a teen mother who abandoned her newborn baby in an alley, as the staffers must make difficult decisions about the teen's future. Also, a hypochondriac with chest pains is treated, as is a patient suffering from possible dementia.

Sharon Goodwin puts her job on the line for a patient in need of a lifesaving bone-marrow transplant. Meanwhile, April cares for a homeless man, Dr. Manning's parents arrive, and a couple are injured during their first date by a hit-and-run driver.

Dr. Rhodes and Dr. Downey clash over how to treat a patient with various health and heart issues. Meanwhile, excessive hoarding at a home comes into play when trying to help a man with a leg injury; a patient is bitten by her own dog; and a commission pays a surprise visit to evaluate the hospital.