Dr. Marcel and Dr. Manning lay everything on the line to assist a sick woman. Dr. Halstead faces an uphill battle in getting participants involved in his clinical trial. Dr. Choi clashes with a patient who demands absolute perfection of himself.

As Maggie deals with her own trauma, she steps in to help a mother in need. Dean continues to stir the pot with more than one doctor. A patient comes to Med needing immediate treatment, but doesn't want it from them.