Things become more dire inside the situation room. Lex becomes more frustrated by the false hope he's forced to send to the public.

As tensions reach a fever pitch inside the cordon, mobs of angry protestors take to the streets in an attempt to break free. Meanwhile, stuck in isolation and cut off from their chain of command, Lex and Dr. Lommers have no choice but to stand by helplessly as the cordon erupts into mass chaos. At the hospital, Jake attempts to lighten the mood by taking Katie on a date, but their happiness is short-lived after they discover that several of Katie’s students have gone missing. Meanwhile, with Lex nowhere to be found, Leo moves forward with their investigation, inching one step closer to uncovering the person responsible for the outbreak.