In this first episode, Piers travels to Gatesville Texas to meet Erin Caffey who, at the age of 16, masterminded the brutal murder of her entire family. For this incomprehensible act, Erin will remain behind bars until she is almost 60 years old and in a gripping encounter behind bars, Piers draws from Erin what made an apparently typical teen-aged girl conspire with her boyfriend to kill her mum, dad and two younger brothers.

In this second episode, Piers meets two very different female murderers, both of whom killed someone they loved.

Piers meets Rebecca Fenton, who was found guilty of murdering her husband Larry Fenton in 2008. Piers meets Rebecca in Lowell Correctional Institution in Florida, for a conversation about what truly happened on that deadly Superbowl Sunday.

Piers meets Amber Wright, who was found guilty of first degree murder at the age of 15 after her ex-boyfriend was found burned and scattered around a rock quarry in Florida.

Jennifer Mee first gained fame as the " Hiccup Girl". She is now serving a life sentence even though she didn't pull the trigger and wasn't even at the scene when the bullets that killed a young man, Shannon Griffin, were fired.

Ashley Humphrey stalked her victim Sandee Rozzo, a woman she did not even know for nearly 20 miles with murder very much on her mind. After shooting her point blank 8 times Ashley is only serving 25 years. Piers Morgan meets with her in prison.

For 14 years, Sheila Davalloo has remained silent about the events surrounding the murder of Anna Lisa Raymundo. But in an exclusive first-ever interview, Piers will get the chance sit face to face with Davalloo and drill down into what really happened.