Hugh finds an unlikely test subject for his revolutionary new artificial heart. Passions are aroused when Charlie and Matt host a wild B&S Ball at their Brewery.

Hugh makes an emergency visit to the city to salvage his career, and learns a family secret that will change his life forever. Charlie's frustration with Meryl's meddling reaches crisis point, and she takes sweet revenge.

Hugh faces a dilemma when his best friend Joey makes a dying wish. The Knight family rallies to support Ajax and Meryl as they each confront a major crisis.

Hugh's world is rocked when Penny accepts a job in the city and the hospital is thrown into chaos. Charlie develops an unhealthy obsession over Hugh's relationship with Penny.