When Kevin O'Neil, a realtor to the stars, is accused of brutally murdering his beautiful wife Caitlin, he hires the firm of Trott, Nicholson, Tuller & Gaines. Spurred on by the court TV show, American Crime, the media have all but convicted him and are out for blood as is the prosecutor. But the lawyers at TNT&G use state-of-the-art forensic interpretation, jury consultants, mock juries, experts, and masterful media spin to defend Kevin. All techniques may be successful as long as the attorneys can cope with the new evidence that seems to keep turning up.

TNT&G takes the case of a young female college student claiming self-defense in the death of a famous music producer who has a history of abusing women. Soon the attorneys believe they might be defending a cold-blooded murderer because she changes her testimony to explain each new, incriminating piece of evidence that is found.