Bartlet continues to struggle over the wisdom of assassinating the terrorist Qumari defense minister; after Ritchie declines to meet Bartlet, Sam and Toby play a dirty trick; as the search for Mrs. Landingham's replacement continues, Charlie finds the perfect candidate, who makes less than a stellar first impression on Bartlet; Josh's determination to pass a welfare bill costs Amy; as C.J.'s stalker is finally captured, the night ends in tragedy.

Donna teaches Toby and Josh an important lesson as their trek homeward continues; Sam staffs the President in Josh's absence and welcomes an old friend home; Bartlet hires a secretary and C.J. finds a Big Brother for Anthony; the situation in Qumar continues to escalate; Bartlet gets spooked by a photo op as the Dow continues its dive; and a pipe bomb kills 44 students at a Midwest university swim meet.

Election day finally arrives with the staff eagerly anticipating the outcome; Sam is increasingly concerned about the Wilde campaign in Orange County; Toby worries about the effect of Andy's pregnancy on the voters; Donna accidentally votes for Richie and tries to rectify the situation by trying to find someone who will vote-swap; Josh resists Deborah's new office rules until she reveals their basis; Bartlet has some new health issues to worry about.

The 15-year old son of an Iranian leader needs a heart transplant in the U.S. Problem is, the only man who could do it is an enemy of the Iranian government; The Senate minority leader threatens to thwart the President's legislative agenda when he believes that Hoynes is doing some political maneuvering for the next Presidential election; Toby offers a Congresswoman a Cabinet position but is forced to take back the offer.

Bartlet plays hardball to end the genocide in Kundu; after the entire speechwriting staff quits, Will is forced to rely on Elsie and some inexperienced interns to write tax policy remarks; the trip to California to help Sam's campaign gets off to a rocky start; Sam refuses to let Bartlet hold off the Democratic response to the Republican tax plan because it might hurt the campaign; Toby and Charlie get arrested coming to Andy's defense after a drunk accosts her; Bartlet fires Sam's campaign manager and replaces him with Toby.

While Toby and C.J. are in California working on Sam's campaign, Josh drops Abbey's agenda in favor of his own, Jed deals with a military hostage situation, and Will runs his intern writing staff ragged.

The White House is locked down after a gunman on the street fires shots into the West Wing; Josh interviews a candidate to replace Ainsley Hayes; Bartlet negotiates for the return of a spy plane is forced down over Russia; the staff plays poker.

As the search for Zoey continues, Walken takes a hard line against the kidnappers that could contribute to her death; Danny releases the Shareef story, and the revelation creates a rift that separates Jed from Abbey and Liz; tensions arise between Walken's staff and Bartlet's staff; the Democratic leadership in Congress assails Leo for allowing Jed to step aside; in retaliation for Shareef's death, a movie theater in Turkey is bombed, and eighty people, including American soldiers, are killed.

When he realizes that his first choice for Vice President faces an uphill fight for nomination, Jed nominates a congressman that none of the staff can get excited about; Josh is less than thrilled with his new intern.

The Bartet clan attempts to gather for a holiday dinner. Jed must deal with a hostage situation in Sudan, an assisted suicide in Oregon, his son-in-law's yearn to run for the House of Representatives, and his grandson's want to spend time with his grandpa. C.J. takes a stand on the assisted suicide because of her father's worsening condition.

When five navy E-2C Hawkeye crew members are stranded in North Korea, Bartlet orders a risky Navy Seal rescue attempt. C.J. agrees to one on one with a motormouth conservative talk show host

When a conservative Republican Congresswoman targets Ellie's research project in an effort to discredit Jed, Toby discovers that the source of the leak is uncomfortably close to home, and Will realizes that they've all greatly underestimated his boss; Josh investigates the wisdom of a recess appointment as he tries to convince an old friend to be patient with the Sixth Circuit judicial nomination process and keep his hat in the ring; C.J. completely misreads Ben's intentions; Donna tracks down an AWOL Ryan; an opening is created on the Supreme Court; in an effort to redefine Abbey's image with the press, C.J. sets her up to do a public service announcement with the Muppets, which inspires Ellie to stand up before the press in defense of scientific research unhampered by politics.

Jed and the staff vet potential Supreme Court appointees; Toby and Andy don't see eye-to-eye on her fact-finding trip to the Middle East; Donna's parents are the unlikely inspiration for the resolution to the problems arising from the judicial confirmation process.

Hail the conquering hero. Josh returns after nailing down details for a trade agreement. But the devil in the detail, including information kept from Josh. C.J. fights megamedia ownership of local TV.

An airborne contamination alert locks down the West Wing, forcing staffers to stay put until the all-clear is sounded; Toby and Will face off over Will's working for the vice president; C.J. tells Donna some things she's rather not hear about Josh and her career prospects; Leo confronts Abbey about the dangers of her recent coping mechanisms; Jed, Debbie, and Charlie are poked, prodded, and sent to the decontamination showers; Kate is initially reluctant to give Josh any information on a personal or professional level as they sit out the alert together.

Jed weighs his options for responding to the bombing as Israeli and Palestinian forces face off against each other; Josh has an interesting reaction when Colin arrives at the hospital to visit Donna; Kate and Leo clash over the advice she's giving Jed; Josh assumes a diplomatic role when the Palestinians approach him to initiate settlement discussions; Toby and Charlie prepare a reluctant Jed for throwing out the first ball at Camden Yards; Donna's life is threatened when she develops a pulmonary embolism; Jed reflects on the days prior to his first inauguration.

As they remain at Donna's bedside while she recuperates from surgery to remove a pulmonary embolism, Colin questions Josh about his personal relationship with Donna. When Bartlet and Leo clash over the appropriate response to the Gaza attack, Kate makes the case for a summit meeting, and provides Bartlet with the hook he needs to get the Israelis and Palestinians to sit down together at Camp David.

Bartlet orders a strike on the terrorist training camp as he and his staff broker a peace settlement between the Israelis and the Palestinians, but Bartlet and Leo realize that their differences over the peace settlement are irreconcilable, warranting a change in Leo's responsibilities. Having returned from Germany, Josh expresses concern about Leo's well-being, and his observations turn out to be well founded.

Leo is rushed into bypass surgery after suffering a massive heart attack; as Toby and Josh scramble chaotically to get votes after Haffley demands Democratic support for a tax cut in exchange for ratification of the peace plan, it becomes quickly apparent that Jed must overcome his reluctance to name a new chief of staff; C.J. works with the State Department on getting U.N. and NATO approval of the peace accord; Charlie drags his feet about completing some minor graduation requirements because he's reluctant to keep his promise that he'll resign as Jed's body man to seek a better position once he has his degree; Donna returns to work; C.J. gets on Josh's case about his unhealthy diet.

Margaret and Charlie prove to be invaluable allies as C.J. has a rough first day in her new position, made even more difficult by a Russian bearing radioactive gifts and a Defense Secretary's attempts to undermine her; Toby's less than stellar performance in the briefing room makes the search for a new press secretary a top priority, and Josh volunteers Donna to assist him in interviewing potential candidates; faced with a number of vulnerable seats in the upcoming election, Josh attempts to dissuade Matthew Santos from dropping out of another race for the House.

The peace mission suffers its first American casualty, whose father is sharply critical of the administration; Santos breaks ranks with the party by signing onto Republican legislation for a patient bill of rights when his own bill dies in committee; Margaret searches for a new office for Charlie; Leo struggles to recover his health, his strength, and his appetite with the help of his nurse, who looks after both his body and his soul with wisdom and determination; Donna, out of her wheelchair and onto crutches, is besieged by the media for interviews; C.J. has harsh words for Toby when he lets his personal feelings take him off-message in the briefing room; Leo contemplates a post-recovery job offer in the private sector before his nurse reminds him why he left there in the first place; Will calls Josh out about the staff's disrespect for Russell's candidacy; as Annabeth finds a way to turn around a bad news cycle, Toby admonishes C.J. about micro-managing the press office.

Hoynes throws his hat in the presidential ring, and asks Josh to join his campaign; Jed's health begins to deteriorate; Toby and Kate head the protocol negotiations with the Chinese over the arrangements for the upcoming summit, which is jeopardized when Jed mistakenly accepts a Taiwanese flag at the National Prayer Breakfast; Bernard takes his new position as head of the Gifts Unit to heart as he gives Charlie a hard time about retrieving the flag so that it can be returned; Josh has his hands full with a pro-Taiwanese senator holding a hard line on recognizing their independence; Bob Russell crashes an Oval Office photo op with the governor of Pennsylvania, who's also another potential presidential candidate.

On the day after Bartlet gives his last State of the Union address, Leo returns to the West Wing but has difficulty getting the attention of the rest of the staff for a meeting about what to do during the remaining 365 days of Barlet's term. Kate and C.J. have to deal with emergencies in Bolivia and North Korea. Charlie tries to figure out how to get Congress to support funding for the Earned Income Tax Credit. Toby solicits Annabeth's advice regarding proper behavior for Abbey at a NASCAR event. Will asks why they originally chose Russell to be Vice President. And Bartlet seems to have recovered most of his strength after his recent bout with MS.

A new candidate for president, Senator Rafferty, has garnered much media attention with a ground-breaking speech about health care. But her words contain interesting echoes of President Bartlet's original health plan, which is known only to White House insiders, and reporter Greg Brock suspects that Rafferty is being secretly supported by the incumbent. Meanwhile, Toby is more than usually morose after the death of his brother. A bill to combat drought conditions in the western U.S. gives C.J. problems, particularly in dealing with lobbyist Clifford Calley. And Charlie tells Kate Harper that a man from his gym asked if she was dating anyone.

New rumors about Fidel Castro's health cause the President to re-examine the economic sanctions against Cuba that haven't worked for 40 years, and he sends Leo McGarry to meet secretly with the Cuban dictator. The occasion causes C.J. to check into Kate Harper's past with the C.I.A., but she is unaware of a past encounter between Kate and Leo. Meanwhile, Charlie discovers the complexities of dealing with a termite invasion of the White House.

At the Democratic National Convention, Russell, Santos and Baker jockey for the 2162 votes that will give one of them the nomination for President, and the opportunity to lose to the apparently unstoppable Vinick in November. Meanwhile, the President must make a decision before it's too late on whether to deploy a secret rescue mission to the space station, and the FBI is asked to determine who leaked the existence of the military shuttle to the press.

Margaret is interrogated at a hearing held by the Senate Select Committee on Intelligence; Santos deflects religious questions onto Vinick; Someone gives C.J. intelligence information; a Palestinian leader is assassinated and Bartlet wants to attend the funeral despite security concerns. Also, we learn Margaret's last name.

Santos is working on campaign strategy, Ellie's getting married, Abbey is welcoming guests, Bartlet's making jokes, China and Kazahkstan are about to go to war, Carol makes an appearance, and Josh may get fired.

After the near-nuclear disaster at the power plant the polls show surprising, or maybe not so surprising, results for both candidates. The Vinick camp gears up for backlash while the Santos camp hopes for cause to celebrate. Meanwhile Bartlet is still trying to keep the situation in Central Asia under control. Relationships in the Santos campaign, the Vinick campaign, and the West Wing all undergo changes and Vinick and Bartlet attempt to deal with different versions of the cold.

Former series regulars, including Marlee Matlin, Mary-Louise Parker, Tim Matheson, Anna Deavere Smith and Gary Cole, make guest appearances as Bartlet, Santos and their staff members attend a funeral for one of their own. Also, Josh cautions Santos about getting involved in the vote for Speaker of the House.

Former cast member Rob Lowe returns as a senior political official in this episode, which finds Bartlet and his staff making the transition as easy as possible for the president-elect, who discovers some unpleasant realities about his new job. Meanwhile, a stressed-out Josh realizes that he may need to take some time off after he reaches his breaking point.

After seven seasons of the Award-winning drama series, the Bartlet Administration prepares to leave the White House and The West Wing. While Santos and his winning camp are nervously gearing up for the presidential inauguration, current President Bartlet (Martin Sheen), CJ (Allison Janney) and the others fondly look back as they prepare to leave the White House forever.