The presidential candidates journey to Iowa, where democrats Russell and Santos, and republican Vinick, are all told by their handlers that when they appear before before the corn growers association they must support subsidies for the use of corn-derived ethanol as fuel, regardless of their true feelings.

Senator Vinick, now the Republican Presidential nominee, receives advice from former Bartlet political consultant Bruno Gianelli on how to win all 50 states in the general election, and more specifically in the near term how to present his religious views to the public and pick a running mate. Meanwhile, Bartlet wrestles with getting a minimum wage hike passed by attaching it to a bill necessary to raise the debt ceiling, and with how to unify his party in the face of a three-way race for the Democratic nomination.

It's three weeks into the presidential campaign and Vinick meets with Frost out on the trail. Santos pulls a stunt which leads to higher approval ratings and jolts the Vinick camp. Vinick and Santos try to kick each other politically while they focus on their messages of the week.

Donna is back and she's working for the Santos/McGarry campaign, but not for Josh. An attack ad on Santos by a pro-life group puts Vinick in a corner when Santos demands Vinick renounce it but Vinick knows that if he does it will offend the G.O.P. leadership.

Santos and Vinick battle it out in primetime live. Forrest Saywer the moderator poses questions and attempts to ensure that the candidates remain within bounds. Ellen DeGeneres guest hosts the show on behalf of American Express and their new credit card.

All eyes are looking forward to the Leo McGarry/Ray Sullivan Vice Presidential debate. Meawhile, Santos is trying not to catch his children's cold and he visits his home in Texas and continues to campaign. Jorge Santos, the Congressman's brother, may cause some problems at a gathering.

After the near-nuclear disaster at the power plant the polls show surprising, or maybe not so surprising, results for both candidates. The Vinick camp gears up for backlash while the Santos camp hopes for cause to celebrate. Meanwhile Bartlet is still trying to keep the situation in Central Asia under control. Relationships in the Santos campaign, the Vinick campaign, and the West Wing all undergo changes and Vinick and Bartlet attempt to deal with different versions of the cold.

Abbey is in New Hamphire with Liz Bartlet-Westin and they are awaiting the results of Doug Westin's campaign for a seat in Congress. Members of both the Santos campaign and the Vinick campaign must decide how to handle a tragedy, as the voters around the country continue to cast their votes for the next President of the United States.

While Santos is busy trying to select a new vice president, his wife finds her new responsibilities staggering. Meanwhile, Vinick ponders his next move.