After Agent May confronts Yo-Yo, Yo-Yo reunites with an old acquaintance and digs up the past.

Yo-Yo finds herself held captive by Ramon and discovers he has a connection to an old foe of S.H.I.E.L.D. When some unexpected help arrives, Yo-Yo gets her chance to exact vengeance against the man who caused her family pain.

Yo-Yo continues her personal mission of vengeance and must decide if she will cross the line and take a life in her quest for revenge. In the aftermath of her covert adventure, Yo-Yo weighs her commitment to the S.H.I.E.L.D. team.