Lynette learns that no good deed goes unpunished when she momentarily befriends the mean Mrs. McClusky. Susan's mother decides to try and jump start her and her daughter's love lives. Andrew talks to a priest about his feelings, and tells him of his shocking plans for his mother, Bree. Gabrielle has her credit card declined in an upscale restaurant, and Carlos sends Gabrielle a big message about what will happen if she leaves him.

The new neighbors, the Applewhites have moved in. Gabrielle, Lynette, and Susan attempt to comfort Bree while Rex's mother arrives on Wisteria Lane for his funeral. Meanwhile Mike and Susan deal with Zach while Gabrielle struggles with the two men in her life.

It's wedding day for Bree and Orson but things don't go quite as planned. Meanwhile, the body of a dead woman believed to be Orson's ex-wife is recovered, which interrupts the reception. Susan goes on a date with Ian, but trouble ensues when his in-laws show up at the restaurant. When Nora breaks up with her boyfriend, Lynette decide to hook up Nora with someone. Edie lets her 18-year-old nephew Austin come live with her for some time. Lastly, Xiao-Mei goes into labor.