After a car crashes into Joe’s Bar, Andy and Sullivan lead the team of firefighters as they work to rescue their fellow crewmates Ben and Pruitt, Grey Sloan doctors and interns, and bar patrons before the building comes crumbling down.

The crossover continues on Grey's Anatomy S16E10 Help Me Through the Night (II).

While Pruitt grieves a monumental loss, Andy refuses to do the same and, instead, throws herself into work. Meanwhile, the crew responds to a widespread carbon monoxide leak, and Sullivan makes a controversial choice for captain.

While at a lunch seeking Pruitt’s blessing for their relationship, Andy and Sullivan jump into action when ICE attempts to raid the restaurant. Meanwhile, Travis gets roped into an awkward lunch with Chief Dixon, Emmett and Emmett’s girlfriend; and Ben invites Grey-Sloan Memorial surgeons Owen Hunt, Teddy Altman and Jackson Avery to get a sneak peek of the new PRT vehicle.