When Theo and Vic hit a relationship milestone, Vic is forced to reckon with her feelings about commitment. Andy takes refuge at Dean’s home and helps care for Pruitt, while Dean considers a new potential career opportunity. Meanwhile, an explosion rips apart a neighborhood and changes the lives of our firefighters forever. The crossover continues on Grey's Anatomy S18E05: Bottle Up and Explode! (II)

Station 19 and Station 23 each attempt to celebrate Thanksgiving following the fallout from the neighborhood explosion. The firefighters come together to cook, toast to loved ones they have lost, and celebrate the families they have become.

Vic and Jack lean on one another as they process the loss of Dean while Ben and Bailey try to convince Dean’s parents to allow them to raise Pru. Meanwhile at Station 23, Andy’s role temporarily expands and Sullivan subs in. Carina and Maya explore growing their family.

A new chief starts at Station 19. Meanwhile, the crew responds to a young girl seeking help and a call about an SUV flown over a cliff. The crossover continues on Grey's Anatomy S18E09: No Time to Die (II)

Travis and Theo face danger while responding to an emergency at a haunted house. Ben continues his fight for Baby Pru; Vic opens up to Andy; and Station 19 prepares to welcome patients to the Dean Miller Memorial Clinic.

The Dean Miller Memorial Clinic has its opening day. Meanwhile, Sullivan gives Beckett an ultimatum, and the crew responds to a skydiving incident

Through a series of flashbacks, Sullivan and Natasha’s past is revealed. Meanwhile, Ben and Bailey have a discussion with Pru’s grandparents, and the crew responds to a fire at a candy factory.

The crew at Station 23 faces a difficult goodbye. Meanwhile, Andy meets a charming firefighter, and Emmett invites Travis to have dinner with his parents.